Zhu Minfang, Zhang Weibin, Lyu Anqi, Gao Juanbi
Department of Neurology, Jiangmen Central Hospital, Jiangmen, China.
Department of Pathology, Jiangmen Central Hospital, Jiangmen, China.
Front Neurol. 2024 Oct 8;15:1435097. doi: 10.3389/fneur.2024.1435097. eCollection 2024.
Acute postoperative urinary retention (POUR) is a common complication in patients with ischemic stroke following femoral artery puncture (FAP), leading to discomfort, delayed hospital discharge, and increased patient morbidity. The relevant risk factors are unclear; thus, a predictive tool is required to guide treatment decisions.
To develop and validate a nomogram to predict acute POUR in patients with ischemic stroke following FAP.
We retrospectively collected cases from 1729 patients with ischemic stroke from the electronic record system of Jiangmen Central Hospital from January 2021 to December 2023. A total of 731 patients were randomly divided into development ( = 511, 70%) and validation ( = 220, 30%) groups. Univariate and multivariate logistic regression analyses with backward stepwise regression were used to select the predictive variables, and a nomogram was developed. The discrimination was evaluated based on the area under the curve (AUC). Calibration was assessed using calibration plots and the Hosmer-Lemeshow test. Clinical applications were evaluated using decision curve analysis (DCA).
The incidence of acute POUR was 12.72%. Preoperative statin use within 24 h, operation type, intraoperative infusion, postoperative water intake within 3 h, postoperative pain, and postoperative anxiety were included in the nomogram. The AUC values were 0.764 [95% confidence interval (CI): 0.705-0.825] in the development group and 0.741 (95% CI: 0.615-0.856) in the validation group. The calibration plots showed good calibration. The values in the Hosmer-Lemeshow tests were 0.962 and 0.315 for the development and validation groups, respectively. The DCA showed that patients could benefit from this nomogram.
A nomogram was developed to successfully predict acute POUR in patients with ischemic stroke following FAP. This nomogram is a convenient and effective tool for clinicians to aid in the prevention and early intervention of acute POUR.
急性术后尿潴留(POUR)是股动脉穿刺(FAP)后缺血性卒中患者的常见并发症,会导致不适、延迟出院以及患者发病率增加。相关危险因素尚不清楚;因此,需要一种预测工具来指导治疗决策。
开发并验证一种列线图,以预测FAP后缺血性卒中患者的急性POUR。
我们从江门市中心医院电子病历系统中回顾性收集了2021年1月至2023年12月期间1729例缺血性卒中患者的病例。总共731例患者被随机分为开发组(n = 511,70%)和验证组(n = 220,30%)。采用单因素和多因素逻辑回归分析及向后逐步回归来选择预测变量,并绘制列线图。基于曲线下面积(AUC)评估辨别力。使用校准图和Hosmer-Lemeshow检验评估校准情况。使用决策曲线分析(DCA)评估临床应用情况。
急性POUR的发生率为12.72%。列线图纳入了术前24小时内使用他汀类药物、手术类型、术中输液、术后3小时内饮水量、术后疼痛和术后焦虑。开发组的AUC值为0.764 [95%置信区间(CI):0.705 - 0.825],验证组为0.741(95% CI:0.615 - 0.856)。校准图显示校准良好。开发组和验证组的Hosmer-Lemeshow检验P值分别为0.962和0.315。DCA表明患者可从此列线图中获益。
开发了一种列线图,成功预测了FAP后缺血性卒中患者的急性POUR。该列线图是临床医生预防和早期干预急性POUR的便捷有效工具。