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温带气候下的亚急性类鼻疽病

Subacute pulmonary melioidosis in a temperate climate.

作者信息

Wilson J W, Ashdown L R, Richards M J, Sutherland A D, Cade J F

出版信息

Med J Aust. 1987 Jul 20;147(2):95-6. doi: 10.5694/j.1326-5377.1987.tb133271.x.

DOI:10.5694/j.1326-5377.1987.tb133271.x
PMID:3600459
Abstract

Previous reports of cases of melioidosis that were seen in nonendemic areas of Australia describe recrudescences of latent infection. We describe the case of a patient who presented in the cooler climate of Melbourne with a probable primary, subacute pulmonary infection with Pseudomonas pseudomallei. This case illustrates several points that bear consideration in the management of atypical pneumonia and, more specifically, pulmonary melioidosis. Historical and occupational clues are easily missed or unrecognized, while a persistent growth of gentamicin-resistant Pseudomonas species should arouse suspicion. Septicaemic melioidosis carries a poor prognosis, and treatment should be early and aggressive; use of the newer, third-generation cephalosporin agents should be considered. Given active support in a well-equipped intensive care unit, together with appropriate antibiotic therapy, patients may eventually be cured of this infection, but a high mortality rate is still encountered.

摘要

先前在澳大利亚非流行地区出现的类鼻疽病例报告描述了潜伏感染的复发情况。我们描述了一名患者的病例,该患者在墨尔本较凉爽的气候中出现了可能由类鼻疽杆菌引起的原发性亚急性肺部感染。该病例说明了在非典型肺炎管理中,更具体地说是在肺类鼻疽管理中需要考虑的几个要点。病史和职业线索很容易被忽视或未被识别,而对庆大霉素耐药的假单胞菌属细菌持续生长应引起怀疑。败血症型类鼻疽预后不良,治疗应尽早且积极;应考虑使用更新的第三代头孢菌素类药物。在设备完善的重症监护病房给予积极支持,并配合适当的抗生素治疗,患者最终可能治愈这种感染,但仍会遇到高死亡率。

相似文献

1
Subacute pulmonary melioidosis in a temperate climate.温带气候下的亚急性类鼻疽病
Med J Aust. 1987 Jul 20;147(2):95-6. doi: 10.5694/j.1326-5377.1987.tb133271.x.
2
Pulmonary melioidosis.肺类鼻疽病
Chest. 1995 Nov;108(5):1420-4. doi: 10.1378/chest.108.5.1420.
3
Pulmonary melioidosis; a diagnostic dilemma and increasing threat.肺类鼻疽;诊断难题与日益严重的威胁。
Ann Thorac Surg. 1969 Jun;7(6):491-9. doi: 10.1016/s0003-4975(10)66386-2.
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Pulmonary melioidosis in febrile neutropenia: the rare and deadly duet.发热性中性粒细胞减少症中的肺类鼻疽:罕见且致命的双重奏。
Trop Doct. 2010 Jul;40(3):165-6. doi: 10.1258/td.2010.090461. Epub 2010 May 17.
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Melioidosis.类鼻疽
Neth J Med. 1999 Feb;54(2):76-9. doi: 10.1016/s0300-2977(98)00129-6.
6
Melioidosis in the Northern Territory of Australia.澳大利亚北领地的类鼻疽病。
Med J Aust. 1981 Feb 21;1(4):181-4. doi: 10.5694/j.1326-5377.1981.tb135443.x.
7
Meliodosis.类鼻疽病
Med J Aust. 1980 Apr 5;1(7):314-6.
8
Melioidosis. Forgotten, but not gone!
Arch Intern Med. 1991 Mar;151(3):605-8. doi: 10.1001/archinte.151.3.605.
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Melioidosis in a patient from Bangladesh.
Postgrad Med J. 1991 Aug;67(790):764-6. doi: 10.1136/pgmj.67.790.764.
10
Pulmonary melioidosis. Observations in thirty-nine cases.肺类鼻疽。39例观察报告。
Am Rev Respir Dis. 1975 Sep;112(3):331-40. doi: 10.1164/arrd.1975.112.3.331.

引用本文的文献

1
Correlates of immune protection following cutaneous immunization with an attenuated Burkholderia pseudomallei vaccine.经皮接种减毒伯克霍尔德氏菌疫苗后免疫保护的相关性研究。
Infect Immun. 2013 Dec;81(12):4626-34. doi: 10.1128/IAI.00915-13. Epub 2013 Oct 7.
2
In vitro activities of the newer beta-lactam and quinolone antimicrobial agents against Pseudomonas pseudomallei.新型β-内酰胺类和喹诺酮类抗菌药物对类鼻疽杆菌的体外活性
Antimicrob Agents Chemother. 1988 Sep;32(9):1435-6. doi: 10.1128/AAC.32.9.1435.
3
Melioidosis: the tip of the iceberg?
类鼻疽:冰山一角?
Clin Microbiol Rev. 1991 Jan;4(1):52-60. doi: 10.1128/CMR.4.1.52.