• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

来自叶片的富含槲皮素-3-O-β-D-吡喃葡萄糖苷的组分可抑制敌敌畏处理的Wistar大鼠大脑中的氧化应激、神经炎症、细胞凋亡和脂质过氧化反应。

Quercetin-3-O-β-D-Glucopyranoside-Rich Fraction from Leaves Halted Responses from Oxidative Stress, Neuroinflammation, Apoptosis, and Lipid Peroxidation in the Brain of Dichlorvos-Treated Wistar Rats.

作者信息

Ogunro Olalekan Bukunmi, Salawu Akeem Oni, Alotaibi Saqer S, Albogami Sarah M, Batiha Gaber El-Saber, Waard Michel De

机构信息

Department of Biological Sciences, Faculty of Applied Sciences, KolaDaisi University, Ibadan 200213, Nigeria.

Department of Biochemistry, Faculty of Life Sciences, University of Ilorin, Ilorin 240222, Nigeria.

出版信息

Toxics. 2022 Aug 16;10(8):477. doi: 10.3390/toxics10080477.

DOI:10.3390/toxics10080477
PMID:36006156
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9413772/
Abstract

Dichlorvos (2,3-dichlorovinyl dimethyl phosphate or DDVP), is a popular organophosphate (OP) with several domestic, industrial, and agricultural uses and applications in developing countries [...].

摘要

敌敌畏（2,3-二氯-2-氯乙烯基二甲基磷酸酯或DDVP）是一种广为人知的有机磷酸酯，在发展中国家有多种家用、工业和农业用途及应用[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/5d07c2bb1726/toxics-10-00477-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/af8561627055/toxics-10-00477-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/1b6acb97c99a/toxics-10-00477-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/51833a660452/toxics-10-00477-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/d79d3499da29/toxics-10-00477-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/64c259598067/toxics-10-00477-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/5d07c2bb1726/toxics-10-00477-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/af8561627055/toxics-10-00477-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/1b6acb97c99a/toxics-10-00477-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/51833a660452/toxics-10-00477-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/d79d3499da29/toxics-10-00477-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/64c259598067/toxics-10-00477-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/9413772/5d07c2bb1726/toxics-10-00477-sch001.jpg

相似文献

1
Quercetin-3-O-β-D-Glucopyranoside-Rich Fraction from Leaves Halted Responses from Oxidative Stress, Neuroinflammation, Apoptosis, and Lipid Peroxidation in the Brain of Dichlorvos-Treated Wistar Rats.来自叶片的富含槲皮素-3-O-β-D-吡喃葡萄糖苷的组分可抑制敌敌畏处理的Wistar大鼠大脑中的氧化应激、神经炎症、细胞凋亡和脂质过氧化反应。
Toxics. 2022 Aug 16;10(8):477. doi: 10.3390/toxics10080477.
2
Effect of quercetin against dichlorvos induced nephrotoxicity in rats.槲皮素对毒死蜱诱导的大鼠肾毒性的影响。
Exp Toxicol Pathol. 2014 Jul;66(4):211-8. doi: 10.1016/j.etp.2014.01.007. Epub 2014 Mar 1.
3
Protective properties of Linn leaves on redox status, cholinergic dysfunction and electrolyte disturbance in cyanide-intoxicated rats.柳叶菜科 Linn 属植物提取物对氰化物中毒大鼠氧化还原状态、胆碱能功能障碍和电解质紊乱的保护作用。
Sci Prog. 2021 Apr-Jun;104(2):368504211011866. doi: 10.1177/00368504211011866.
4
seed oil partially abrogates 2,3-dichlorovinyl dimethyl phosphate (Dichlorvos)-induced cardiac injury in rats: evidence for the role of oxidative stress.菜籽油部分阻断 2,3-二氯-1-(二甲基氧膦基)乙烯（敌敌畏）诱导的大鼠心脏损伤：氧化应激的作用证据。
J Basic Clin Physiol Pharmacol. 2020 Nov 3;32(3):237-246. doi: 10.1515/jbcpp-2019-0313.
5
Impaired mitochondrial energy metabolism and neuronal apoptotic cell death after chronic dichlorvos (OP) exposure in rat brain.大鼠脑长期暴露于敌敌畏（有机磷）后线粒体能量代谢受损及神经元凋亡性细胞死亡
Neurotoxicology. 2007 Nov;28(6):1208-19. doi: 10.1016/j.neuro.2007.08.001. Epub 2007 Aug 7.
6
Fish tolerance to organophosphate-induced oxidative stress is dependent on the glutathione metabolism and enhanced by N-acetylcysteine.鱼类对有机磷诱导的氧化应激的耐受性取决于谷胱甘肽代谢，并可被N-乙酰半胱氨酸增强。
Aquat Toxicol. 2003 Dec 10;65(4):337-60. doi: 10.1016/s0166-445x(03)00148-6.
7
Increased oxidative stress is associated with the development of organophosphate-induced delayed neuropathy.氧化应激增加与有机磷诱导迟发性神经病的发展有关。
Hum Exp Toxicol. 2012 Dec;31(12):1214-27. doi: 10.1177/0960327112446842. Epub 2012 Jun 29.
8
Quercetin-3-O-β-D-glucopyranoside-rich fraction demonstrated efficacy against infectious, secretory, and osmotic models of diarrhoeal rats.富含槲皮素-3-O-β-D-吡喃葡萄糖苷的组分对腹泻大鼠的感染性、分泌性和渗透性模型显示出疗效。
J Genet Eng Biotechnol. 2023 Mar 21;21(1):36. doi: 10.1186/s43141-023-00489-7.
9
Cardiotoxic effects of dichlorvos (DDVP) in albino rats.
Indian J Physiol Pharmacol. 1987 Jan-Mar;31(1):19-24.
10
Lycopene attenuates dichlorvos-induced oxidative damage and hepatotoxicity in rats.番茄红素减轻敌敌畏诱导的大鼠氧化损伤和肝毒性。
Hum Exp Toxicol. 2016 Jun;35(6):654-65. doi: 10.1177/0960327115597981. Epub 2015 Jul 30.

引用本文的文献

1
Exploring the Neuroprotective Potentials of Flavonoid Metabolites in : A Review with in-silico Insight to Therapeutic Potential.探索黄酮类代谢产物的神经保护潜力：基于计算机模拟对治疗潜力的综述
J Exp Pharmacol. 2025 Aug 29;17:587-611. doi: 10.2147/JEP.S536765. eCollection 2025.
2
Monosodium glutamate exacerbated the lipopolysaccharide-induced reproductive toxicity of male Wistar rats.味精加剧了脂多糖诱导的雄性Wistar大鼠的生殖毒性。
BMC Pharmacol Toxicol. 2025 Aug 1;26(1):140. doi: 10.1186/s40360-025-00982-4.
3
Neuroinflammatory Response and Redox-regulation Activity of Hyperoside in Manganese-induced Neurotoxicity Model of Wistar Rats.

本文引用的文献

1
Oxidative Stress in the Brain: Basic Concepts and Treatment Strategies in Stroke.大脑中的氧化应激：中风的基本概念与治疗策略
Antioxidants (Basel). 2021 Nov 25;10(12):1886. doi: 10.3390/antiox10121886.
2
The laboratory rat: Age and body weight matter.实验大鼠：年龄和体重很重要。
EXCLI J. 2021 Sep 23;20:1431-1445. doi: 10.17179/excli2021-4072. eCollection 2021.
3
Acetylcholinesterase Inhibitors in the Treatment of Neurodegenerative Diseases and the Role of Acetylcholinesterase in their Pathogenesis.乙酰胆碱酯酶抑制剂在神经退行性疾病治疗中的作用及其在发病机制中的作用。
金丝桃苷在锰诱导的Wistar大鼠神经毒性模型中的神经炎症反应及氧化还原调节活性
Curr Aging Sci. 2024;17(3):220-236. doi: 10.2174/0118746098277166231204103616.
4
The potential therapeutic effect of phosphodiesterase 5 inhibitors in the acute ischemic stroke (AIS).磷酸二酯酶 5 抑制剂在急性缺血性脑卒中（AIS）中的潜在治疗效果。
Mol Cell Biochem. 2024 May;479(5):1267-1278. doi: 10.1007/s11010-023-04793-1. Epub 2023 Jul 3.
Int J Mol Sci. 2021 Aug 27;22(17):9290. doi: 10.3390/ijms22179290.
4
Neuroinflammation in neurological disorders: pharmacotherapeutic targets from bench to bedside.神经疾病中的神经炎症：从 bench 到 bedside 的药物治疗靶点
Metab Brain Dis. 2021 Oct;36(7):1591-1626. doi: 10.1007/s11011-021-00806-4. Epub 2021 Aug 13.
5
Ferroptosis: mechanisms and links with diseases.铁死亡：机制与疾病的关联。
Signal Transduct Target Ther. 2021 Feb 3;6(1):49. doi: 10.1038/s41392-020-00428-9.
6
HOW DOES MY BRAIN COMMUNICATE WITH MY BODY?我的大脑如何与身体进行沟通？
Front Young Minds. 2020 Oct;8. doi: 10.3389/frym.2020.540970. Epub 2020 Oct 22.
7
Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease.乙酰胆碱酯酶抑制剂在阿尔茨海默病中的疗效。
Neuropharmacology. 2021 Jun 1;190:108352. doi: 10.1016/j.neuropharm.2020.108352. Epub 2020 Oct 6.
8
The role of prolyl oligopeptidase, understanding the puzzle.脯氨酰寡肽酶的作用：解读谜团
Ann Transl Med. 2020 Aug;8(16):983. doi: 10.21037/atm-20-3412.
9
Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases.生活方式、氧化应激与抗氧化剂：慢性病病理生理学中的反复作用
Front Physiol. 2020 Jul 2;11:694. doi: 10.3389/fphys.2020.00694. eCollection 2020.
10
Targeting Myeloperoxidase (MPO) Mediated Oxidative Stress and Inflammation for Reducing Brain Ischemia Injury: Potential Application of Natural Compounds.靶向髓过氧化物酶（MPO）介导的氧化应激和炎症以减轻脑缺血损伤：天然化合物的潜在应用
Front Physiol. 2020 May 19;11:433. doi: 10.3389/fphys.2020.00433. eCollection 2020.