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衡量社交距离、检测和未检出无症状病例对 COVID-19 传播的影响。

Measuring the impact of social-distancing, testing, and undetected asymptomatic cases on the diffusion of COVID-19.

机构信息

Department of Entrepreneurship and Small Business, Soongsil University, Seoul, Republic of Korea.

出版信息

PLoS One. 2022 Aug 25;17(8):e0273469. doi: 10.1371/journal.pone.0273469. eCollection 2022.

Abstract

The key to overcoming COVID-19 lies, arguably, in the diffusion process of confirmed cases. In view of this, this study has two main aims: first, to investigate the unique characteristics of COVID-19-for the existence of asymptomatic cases-and second, to determine the best strategy to suppress the diffusion of COVID-19. To this end, this study proposes a new compartmental model-the SICUR model-which can address undetected asymptomatic cases and considers the three main drivers of the diffusion of COVID-19: the degree of social distancing, the speed of testing, and the detection rate of infected cases. Taking each country's situation into account, it is suggested that susceptible cases can be classified into two categories based on their sources of occurrence: internal and external factors. The results show that the ratio of undetected asymptomatic cases to infected cases will, ceteris paribus, be 6.9% for South Korea and 22.4% for the United States. This study also quantitatively shows that to impede the diffusion of COVID-19: firstly, strong social distancing is necessary when the detection rate is high, and secondly, fast testing is effective when the detection rate is low.

摘要

克服 COVID-19 的关键,或许在于确诊病例的扩散过程。有鉴于此,本研究有两个主要目的:首先,调查 COVID-19 的独特特征——存在无症状病例;其次,确定抑制 COVID-19 扩散的最佳策略。为此,本研究提出了一个新的隔室模型——SICUR 模型,该模型可以解决未被发现的无症状病例,并考虑 COVID-19 扩散的三个主要驱动因素:社交距离程度、检测速度和感染病例的检测率。考虑到每个国家的情况,建议根据其发生源将易感病例分为两类:内部和外部因素。研究结果表明,在其他条件相同的情况下,韩国未被发现的无症状病例与感染病例的比例将为 6.9%,而美国则为 22.4%。本研究还定量表明,要阻止 COVID-19 的扩散:首先,当检测率高时,需要强有力的社交距离;其次,当检测率低时,快速检测是有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01c2/9409553/bebd368598b8/pone.0273469.g001.jpg

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