Jusko Maciej, Kasprzak Piotr, Majos Alicja, Kuczmik Waclaw
Department of General Surgery, Vascular Surgery, Angiology and Phlebology, Medical University of Silesia, 40-055 Katowice, Poland.
Department of Vascular Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.
Biomedicines. 2022 Aug 17;10(8):1997. doi: 10.3390/biomedicines10081997.
A ruptured abdominal aortic aneurysm is a severe condition associated with high mortality. Currently, the most important criterion used to estimate the risk of its rupture is the size of the aneurysm, but due to patients' anatomical variability, many aneurysms have a high risk of rupture with a small aneurysm size. We asked ourselves whether individual differences in anatomy could be taken into account when assessing the risk of rupture.
Based on the CT scan image, aneurysm and normal aorta diameters were collected from 186 individuals and compared in patients with ruptured and unruptured aneurysms. To take into account anatomical differences between patients, diameter ratios were calculated by dividing the aneurysm diameter by the diameter of the normal aorta at various heights, and then further comparisons were made.
It was found that the calculated ratios differ between patients with ruptured and unruptured aneurysms. This observation is also present in patients with small aneurysms, with its maximal size below the level that indicates the need for surgical treatment. For small aneurysms, the ratios help us to estimate the risk of rupture better than the maximum sac size (AUC: 0.783 vs. 0.650).
The calculated ratios appear to be a valuable feature to indicate which of the small aneurysms have a high risk of rupture. The obtained results suggest the need for further confirmation of their usefulness in subsequent groups of patients.
腹主动脉瘤破裂是一种死亡率很高的严重病症。目前,用于评估其破裂风险的最重要标准是动脉瘤的大小,但由于患者的解剖结构存在差异,许多动脉瘤在尺寸较小时就具有较高的破裂风险。我们不禁思考,在评估破裂风险时是否可以考虑个体解剖差异。
基于CT扫描图像,收集了186名个体的动脉瘤和正常主动脉直径,并在动脉瘤破裂和未破裂的患者中进行比较。为了考虑患者之间的解剖差异,通过将动脉瘤直径除以不同高度处正常主动脉的直径来计算直径比,然后进行进一步比较。
发现计算出的比值在动脉瘤破裂和未破裂的患者之间存在差异。这种差异在小动脉瘤患者中也存在,其最大尺寸低于表明需要手术治疗的水平。对于小动脉瘤,这些比值比最大瘤体尺寸能更好地帮助我们估计破裂风险(曲线下面积:0.783对0.650)。
计算出的比值似乎是一个有价值的特征,可用于指示哪些小动脉瘤具有较高的破裂风险。所得结果表明需要在后续患者群体中进一步证实其有用性。