Maglione Marco, Pascarella Antonia, Botti Chiara, Ricci Giuseppe, Morelli Fiorella, Camelia Fabiana, Micillo Alberto, Calì Camilla, Savoia Fabio, Tipo Vincenzo, Giannattasio Antonietta
Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
Laboratory of Clinical Pathology, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
Children (Basel). 2022 Aug 17;9(8):1242. doi: 10.3390/children9081242.
Several reports highlighted how public health measures aimed at limiting severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) circulation have likely contributed to reducing the circulation of other respiratory viruses, particularly during the first year of the COVID-19 pandemic. We evaluated the epidemiology of acute respiratory infections in a large cohort of hospitalized children during the third year of the pandemic (2021−2022). We retrospectively analyzed data from the health records of children (<14 years) hospitalized for acute respiratory infections between 1 July 2021 and 31 March 2022. A total of 1763 respiratory panels were collected. Overall, 1269 (72%) panels hadpositive results for at least one pathogen. Most positive panels (53.8%) belonged to patients aged 1−12 months. The most detected pathogen was respiratory syncytial virus (RSV) (57.8% of positive panels). The RSV peak occurred in November 2021. Nine hundred and forty-five (74.5%) panels were positive for one pathogen while three hundred and twenty-four (25.5%) showed multiple infections. Patients with multiple infections were significantly older than those with a single infection. The 2021−2022 peak of RSV infection in Italy occurred earlier than in the previous pre-pandemic seasons. A high number of children have been hospitalized because of acute viral infections also due to less aggressive viruses.
几份报告强调，旨在限制严重急性呼吸综合征冠状病毒2（SARS-CoV-2）传播的公共卫生措施可能有助于减少其他呼吸道病毒的传播，特别是在新冠疫情的第一年。我们评估了疫情第三年（2021 - 2022年）一大群住院儿童的急性呼吸道感染流行病学情况。我们回顾性分析了2021年7月1日至2022年3月31日期间因急性呼吸道感染住院的14岁以下儿童的健康记录数据。共收集了1763份呼吸道样本检测结果。总体而言，1269份（72%）样本至少对一种病原体检测呈阳性。大多数呈阳性的样本（53.8%）来自1至12个月大的患者。检测到最多的病原体是呼吸道合胞病毒（RSV）（占阳性样本的57.8%）。RSV感染高峰出现在2021年11月。945份（74.5%）样本对一种病原体呈阳性，而324份（25.5%）显示多重感染。多重感染的患者比单一感染的患者年龄明显更大。2021 - 2022年意大利RSV感染高峰比疫情前的季节出现得更早。大量儿童因急性病毒感染住院，其中也包括一些致病性较弱的病毒。
