Department of Preventive Dentistry, Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Department of Developmental and Surgical Sciences, Division of Periodontology, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USA.
Int J Environ Res Public Health. 2022 Aug 15;19(16):10061. doi: 10.3390/ijerph191610061.
The use of herbal products in oral cavity has shown an increased popularity and potential benefits due to their additional anti-inflammatory and antioxidant properties as well as the lack of side effects related to their use.
To assess the clinical effectiveness of herbal dental products (mouthwash, dentifrice, gel) when compared to conventional products or placebo in periodontitis patients.
A systematic review with 22 studies was carried out using MEDLINE/Pubmed, EMBASE and Web of Science databases in addition to hand searches. Randomized and non-randomized clinical trials that evaluated the effect of any herbal dental product and compared it with conventional products or placebo in periodontitis patients and published up to March 2022, were screened.
Herbal products used as adjuncts to scaling and root planing (SRP) or supragingival debridement (SPD) led to superior clinical outcomes than placebo or no adjuncts (8 studies). In conjunction with SRP, these products showed comparable outcomes with chlorhexidine (6 studies) or better (4 studies). When used as adjuncts to SPD, herbal oral care products demonstrated comparable outcomes with chlorhexidine and conventional products (4 studies).
Within the limitations of this systematic review, herbal oral care products may play a key role in the management of periodontal disease. Further well-designed studies are needed to establish their efficacy.
由于草药产品具有额外的抗炎和抗氧化特性，且使用时没有相关副作用，因此在口腔中使用草药产品的普及度和潜在益处有所增加。
评估与常规产品或安慰剂相比，草药牙科产品（漱口水、牙膏、凝胶）在牙周炎患者中的临床效果。
通过 MEDLINE/Pubmed、EMBASE 和 Web of Science 数据库以及手工检索，进行了一项包含 22 项研究的系统评价。筛选了评价任何一种草药牙科产品效果并将其与牙周炎患者的常规产品或安慰剂进行比较，且发表时间截至 2022 年 3 月的随机和非随机临床试验。
作为龈下刮治和根面平整（SRP）或龈上洁治术（SPD）的辅助治疗，与安慰剂或无辅助治疗相比，草药产品具有更好的临床效果（8 项研究）。与 SRP 联合使用时，这些产品与洗必泰（6 项研究）或优于洗必泰（4 项研究）具有可比的效果。作为 SPD 的辅助治疗，草药口腔护理产品与洗必泰及常规产品具有可比的效果（4 项研究）。
在本系统评价的限制范围内，草药口腔护理产品可能在牙周病的治疗中发挥关键作用。需要进一步进行设计良好的研究来确定其疗效。
