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白内障患者晶状体、房水和血浆中微量元素水平-叙述性综述。

Levels of Trace Elements in the Lens, Aqueous Humour, and Plasma of Cataractous Patients-A Narrative Review.

机构信息

Department of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24a, 15-276 Bialystok, Poland.

Department of Bromatology, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Mickiewicza 2D, 15-222 Bialystok, Poland.

出版信息

Int J Environ Res Public Health. 2022 Aug 20;19(16):10376. doi: 10.3390/ijerph191610376.

Abstract

Cataracts are one of the most common causes of effective vision loss. Although most cases of cataracts are related to the ageing process, identifying modifiable risk factors can prevent their onset or progression. Many studies have suggested that micro and macroelement levels, not only in blood serum but also in the lens and aqueous humour, may affect the risk of the occurrence and severity of cataracts. This systematic review aims to summarise existing scientific reports concerning the importance of trace elements in cataractogenesis. Many authors have pointed out elevated or decreased levels of particular elements in distinct ocular compartments. However, it is not known if these alterations directly affect the increased risk of cataract occurrence. Further studies are needed to show whether changes in the levels of these elements are correlated with cataract severity and type. Such information would be useful for determining specific recommendations for micronutrient supplementation in preventing cataractogenesis.

摘要

白内障是导致有效视力丧失的最常见原因之一。尽管大多数白内障病例与衰老过程有关,但确定可改变的危险因素可以预防其发生或进展。许多研究表明,微量元素水平,不仅在血清中,而且在晶状体和房水中,可能会影响白内障发生和严重程度的风险。本系统综述旨在总结现有关于微量元素在白内障形成中的重要性的科学报告。许多作者指出,在不同的眼内区域存在特定元素的升高或降低水平。然而,尚不清楚这些改变是否直接影响白内障发生风险的增加。需要进一步的研究来表明这些元素水平的变化是否与白内障的严重程度和类型相关。这些信息对于确定预防白内障形成的特定微量营养素补充建议将非常有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef28/9408557/ab820e39f48c/ijerph-19-10376-g001.jpg

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