Porter J B, Jick H, Walker A M
Obstet Gynecol. 1987 Jul;70(1):29-32.
The occurrence of fatal conditions was substantially similar in a large population of recent, healthy oral contraceptive users and comparable nonusers at Group Health Cooperative of Puget Sound during the years 1977-1981. There were no deaths from cardiovascular disease among those who were oral contraceptive users at the onset of their cardiovascular illness; there was one death from liver cancer, probably attributable to oral contraceptive use; and there were no deaths from complications of pregnancy among either users or nonusers. Newer formulations of oral contraceptives and greater care in prescribing oral contraceptives to the healthiest younger women may have substantially lessened the risks identified with earlier preparations and prescription practices.
在1977年至1981年期间，普吉特海湾集团健康合作社的大量近期健康口服避孕药使用者和可比的非使用者中，致命疾病的发生率基本相似。在心血管疾病发作时使用口服避孕药的人群中，没有因心血管疾病死亡的病例；有1例死于肝癌，可能归因于口服避孕药的使用；使用者和非使用者中均没有因妊娠并发症死亡的病例。新型口服避孕药以及在为最健康的年轻女性开口服避孕药时更加谨慎，可能已大幅降低了早期制剂和处方做法所带来的风险。
