Lin Siyu, Morgant Marie-Catherine, Marín-Castrillón Diana M, Bernard Chloé, Boucher Arnaud, Presles Benoît, Lalande Alain, Bouchot Olivier
IFTIM, ImViA Laboratory, University of Burgundy, 21078 Dijon, France.
Department of Cardio-Vascular and Thoracic Surgery, University Hospital of Dijon, 21078 Dijon, France.
J Clin Med. 2022 Aug 20;11(16):4897. doi: 10.3390/jcm11164897.
Association of quadricuspid aortic valve (QAV) with ascending aortic aneurysms (AsAA) is rare. A 63-year-old female with hypertension was found (on MRI) to have an ascending aortic aneurysm (52 mm in maximum diameter) and dilatation at the level of the sinotubular junction (38 mm in diameter) associated with quadricuspid aortic valve. An ascending aortic wall replacement surgery was performed. In this study, we focus on the behavior of the aorta associated with QAV considering the in vitro biomechanical characteristics and histology. The properties of QAV are closer to bicuspid aortic valve than tricuspid aortic valve, but with higher wall thickness.
四叶式主动脉瓣（QAV）与升主动脉瘤（AsAA）的关联较为罕见。一名63岁患有高血压的女性（经MRI检查）被发现患有升主动脉瘤（最大直径52毫米）以及与四叶式主动脉瓣相关的窦管交界处扩张（直径38毫米）。实施了升主动脉壁置换手术。在本研究中，我们结合体外生物力学特性和组织学，着重关注与QAV相关的主动脉的表现。QAV的特性比三叶式主动脉瓣更接近二叶式主动脉瓣，但具有更厚的壁。
