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人类主动脉和肺动脉中胶原蛋白和弹性蛋白含量的年龄依赖性变化。

Age-dependent changes of collagen and elastin content in human aorta and pulmonary artery.

作者信息

Hosoda Y, Kawano K, Yamasawa F, Ishii T, Shibata T, Inayama S

出版信息

Angiology. 1984 Oct;35(10):615-21. doi: 10.1177/000331978403501001.

DOI:10.1177/000331978403501001
PMID:6497045
Abstract

Collagen and elastin in the arterial wall are thought to show some age-dependent changes, and to relate with development of the arteriosclerotic lesion. Both aortas and the pulmonary trunks were collected from 137 autopsy cases. Biochemical determination of collagen and elastin content was carried out. Collagen and elastin of the aorta and the pulmonary artery showed no significant age-dependent changes. Elastin content of the pulmonary artery increases with age in the adult. This paper seems to be the first report of simultaneous estimation of collagen and elastin content of both the aorta and the pulmonary artery.

摘要

动脉壁中的胶原蛋白和弹性蛋白被认为会呈现一些随年龄变化的改变,并与动脉粥样硬化病变的发展相关。从137例尸检病例中采集了主动脉和肺动脉。对胶原蛋白和弹性蛋白含量进行了生化测定。主动脉和肺动脉的胶原蛋白和弹性蛋白未显示出明显的随年龄变化的改变。在成年人中,肺动脉的弹性蛋白含量随年龄增加。本文似乎是首次同时评估主动脉和肺动脉中胶原蛋白和弹性蛋白含量的报告。

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Angiology. 1984 Oct;35(10):615-21. doi: 10.1177/000331978403501001.
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