Jorge Helena, Duarte Isabel C, Baptista Carla, Relvas Ana Paula, Castelo-Branco Miguel
Coimbra Institute for Biomedical Imaging and Translational Research, CIBIT/ICNAS, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal.
PIDFIF-Inter-University PhD Program in Clinical Psychology, Family Psychology and Family Intervention, Faculty of Psychology and Educational Sciences of Coimbra, Faculty of Psychology of Lisbon, 1649-013 Lisboa, Portugal.
J Pers Med. 2022 Jul 28;12(8):1236. doi: 10.3390/jpm12081236.
Theoretical accounts on social decision-making under uncertainty postulate that individual risk preferences are context dependent. Generalization of models of decision-making to dyadic interactions in the personal health context remain to be experimentally addressed. In economic utility-based models, interactive behavioral games provide a framework to investigate probabilistic learning of sequential reinforcement. Here, we model an economic trust game in the context of a chronic disease (Diabetes Type 1) which involves iterated daily decisions in complex social contexts. Ninety-one patients performed experimental trust games in both economic and health settings and were characterized by a multiple self-report set of questionnaires. We found that although our groups can correctly infer pay-off contingencies, they behave differently because patients with a biological profile of preserved glycemic control show adaptive choice behavior both in economic and health domains. On the other hand, patients with a biological profile of loss of glycemic control presented a contrasting behavior, showing non-adaptive choices on both contexts. These results provide a direct translation from neuroeconomics to decision-making in the health domain and biological risk profiles, in a behavioral setting that requires difficult and self-consequential decisions with health impact. Our findings also provide a contextual generalization of mechanisms underlying individual decision-making under uncertainty.
关于不确定性下社会决策的理论解释假定个体风险偏好取决于情境。将决策模型推广到个人健康背景下的二元互动仍有待通过实验来解决。在基于经济效用的模型中，交互式行为博弈为研究顺序强化的概率学习提供了一个框架。在此，我们在慢性病（1型糖尿病）背景下对一个经济信任博弈进行建模，该博弈涉及在复杂社会情境中反复进行的日常决策。91名患者在经济和健康环境中都进行了实验性信任博弈，并通过多套自我报告问卷进行了特征描述。我们发现，尽管我们的研究对象能够正确推断收益的偶然性，但他们的行为却有所不同，因为血糖控制良好的患者在经济和健康领域都表现出适应性选择行为。另一方面，血糖控制不佳的患者则表现出相反的行为，在两种情境中都表现出非适应性选择。这些结果在一个需要做出困难且对健康有影响的自我决策的行为环境中，实现了从神经经济学到健康领域决策和生物风险特征的直接转化。我们的研究结果还对不确定性下个体决策的潜在机制进行了情境化概括。
