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哥伦比亚犬类衍生抗原和特异性抗体的全国血清流行率调查。

Nationwide Seroprevalence Survey of Derived Antigens and Specific Antibodies in Dogs from Colombia.

作者信息

Uribe Manuel, Segeritz Lisa, Schnyder Manuela, Taubert Anja, Hermosilla Carlos, López-Osorio Sara, Góngora-Orjuela Agustín, Chaparro-Gutiérrez Jenny J

机构信息

Biomedical Research Center Seltersberg (BFS), Institute of Parasitology, Justus Liebig University Giessen, 35392 Gießen, Germany.

CIBAV Research Group, Veterinary Medicine School, Universidad de Antioquia, Medellín 050034, Colombia.

出版信息

Microorganisms. 2022 Aug 4;10(8):1565. doi: 10.3390/microorganisms10081565.

Abstract

is a cardiopulmonary nematode, causing several clinical manifestations in dogs, e.g., severe respiratory signs, coagulopathy, and gastrointestinal or neurological signs. In the last decades, this parasite has been described to spread and emerge in Europe and North America. Scant studies on occurrence in South America exist. Recently, was detected in gastropod intermediate hosts in Colombia, where data on definitive host prevalence, e.g., dogs and wild canids, are still limited. Therefore, the sera of 955 dogs, varying in age and breed from seven different departments all over Colombia, were collected and analysed for antigens and parasite-specific antibodies by ELISA. In total, 1.05 % ( = 10; 95 % CI 0.40-1.69) of the samples were antigen-positive and 2.62 % ( = 25; 95 % CI 1.61-3.63) were antibody-positive. These results confirm the presence of in Colombia, although positive results in antigen and antibody reactions in the same dog were not detected. This study is the first large-scale survey on seroprevalences in dogs from Colombia.

摘要

是一种心肺线虫,可在犬类中引发多种临床表现,例如严重的呼吸道症状、凝血病以及胃肠道或神经症状。在过去几十年中,这种寄生虫已在欧洲和北美被描述为有传播和出现的情况。关于其在南美洲出现情况的研究很少。最近,在哥伦比亚的腹足类中间宿主中检测到了该寄生虫,而关于终末宿主(如犬类和野生犬科动物)患病率的数据仍然有限。因此,收集了来自哥伦比亚七个不同省份、年龄和品种各异的955只犬的血清,并通过ELISA法分析了其抗原和寄生虫特异性抗体。总体而言,1.05%(n = 10;95%可信区间0.40 - 1.69)的样本抗原呈阳性,2.62%(n = 25;95%可信区间1.61 - 3.63)的样本抗体呈阳性。这些结果证实了哥伦比亚存在该寄生虫,尽管未在同一只犬中检测到抗原和抗体反应均呈阳性的情况。本研究是对哥伦比亚犬类中该寄生虫血清阳性率的首次大规模调查。

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