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噬菌体vB_YenS_P400,一种从鹿体内分离出的新型烈性长尾噬菌体。

Phage vB_YenS_P400, a Novel Virulent Siphovirus of Isolated from Deer.

作者信息

Hammerl Jens A, Barac Andrea, Jäckel Claudia, Fuhrmann Julius, Gadicherla Ashish, Hertwig Stefan

机构信息

Department of Biological Safety, German Federal Institute for Risk Assessment, Max-Dohrn Str. 8-10, D-10589 Berlin, Germany.

出版信息

Microorganisms. 2022 Aug 19;10(8):1674. doi: 10.3390/microorganisms10081674.

Abstract

Phage vB_YenS_P400 isolated from deer, is a virulent siphovirus of , whose circularly permutated genome (46,585 bp) is not substantially related to any other phage deposited in public nucleotide databases. vB_YenS_P400 showed a very narrow host range and exclusively lysed two B4/O:3 strains. Moreover, lytic activity by this phage was only discernible at room temperature. Together with the finding that vB_YenS_P400 revealed a long latent period (90 to 100 min) and low burst size (five to ten), it is not suitable for applications but provides insight into the diversity of phages.

摘要

从鹿身上分离出的噬菌体vB_YenS_P400是一种烈性肌尾噬菌体,其环状排列基因组(46,585碱基对)与公共核苷酸数据库中存放的任何其他噬菌体均无实质关联。vB_YenS_P400表现出非常狭窄的宿主范围,仅能裂解两株B4/O:3菌株。此外,该噬菌体的裂解活性仅在室温下可察觉。连同vB_YenS_P400显示出较长潜伏期(90至100分钟)和较低裂解量(5至10)这一发现,它不适合应用,但有助于深入了解噬菌体的多样性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5454/9412545/6ed4f1f9f4c7/microorganisms-10-01674-g001.jpg

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