Hammerl Jens A, Barac Andrea, Jäckel Claudia, Fuhrmann Julius, Gadicherla Ashish, Hertwig Stefan
Department of Biological Safety, German Federal Institute for Risk Assessment, Max-Dohrn Str. 8-10, D-10589 Berlin, Germany.
Microorganisms. 2022 Aug 19;10(8):1674. doi: 10.3390/microorganisms10081674.
Phage vB_YenS_P400 isolated from deer, is a virulent siphovirus of , whose circularly permutated genome (46,585 bp) is not substantially related to any other phage deposited in public nucleotide databases. vB_YenS_P400 showed a very narrow host range and exclusively lysed two B4/O:3 strains. Moreover, lytic activity by this phage was only discernible at room temperature. Together with the finding that vB_YenS_P400 revealed a long latent period (90 to 100 min) and low burst size (five to ten), it is not suitable for applications but provides insight into the diversity of phages.
从鹿身上分离出的噬菌体vB_YenS_P400是一种烈性肌尾噬菌体，其环状排列基因组（46,585碱基对）与公共核苷酸数据库中存放的任何其他噬菌体均无实质关联。vB_YenS_P400表现出非常狭窄的宿主范围，仅能裂解两株B4/O:3菌株。此外，该噬菌体的裂解活性仅在室温下可察觉。连同vB_YenS_P400显示出较长潜伏期（90至100分钟）和较低裂解量（5至10）这一发现，它不适合应用，但有助于深入了解噬菌体的多样性。
