Lange W R, Warnock-Eckhart E
Pediatr Infect Dis J. 1987 May;6(5):447-50. doi: 10.1097/00006454-198705000-00006.
In 1985 there were approximately 8500 international adoptions in the United States, a phenomenon that has doubled in the past 5 years. The majority of these children originate from areas of the world where the hepatitis B virus is hyperendemic and where the prevalence of numerous other infectious diseases is higher than it is domestically. We consecutively screened 360 adopted Korean children for hepatitis B virus markers, syphilis serology, tuberculin status and the presence of parasitic infection. Ten hepatitis B virus carriers were identified (prevalence, 2.8%) as were two children with congenital syphilis and two with reactive tuberculin skin tests. Intestinal parasitosis was not evident but four cases of scabies were detected and were associated with prior residence in an orphanage. We conclude that even though the seroprevalence rate was lower than expected, providers responsible for the care of Korean adoptees should screen for the hepatitis B surface antigen carrier state, that susceptible household contacts of hepatitis B surface antigen-positive children should be protected with hepatitis B vaccine and that children treated abroad for congenital syphilis should be assessed for the adequacy of therapy.
1985年，美国约有8500例国际收养，这一现象在过去5年中翻了一番。这些儿童大多来自世界上乙肝病毒高度流行且许多其他传染病患病率高于美国国内的地区。我们连续对360名收养的韩国儿童进行了乙肝病毒标志物、梅毒血清学、结核菌素状态及寄生虫感染情况的筛查。发现10名乙肝病毒携带者（患病率为2.8%）、2名先天性梅毒患儿和2名结核菌素皮肤试验呈阳性的儿童。未发现肠道寄生虫病，但检测到4例疥疮，均与曾在孤儿院居住有关。我们得出结论，尽管血清阳性率低于预期，但负责照顾韩国收养儿童的机构应筛查乙肝表面抗原携带者状态，乙肝表面抗原阳性儿童的易感家庭接触者应接种乙肝疫苗进行保护，在国外接受先天性梅毒治疗的儿童应评估治疗是否充分。
