Department of Medical, Surgical & Health Sciences, University of Trieste, 34127 Trieste, Italy.
Public Health Department, University Health Agency Giuliano-Isontina (ASUGI), 34148 Trieste, Italy.
Viruses. 2022 Jul 28;14(8):1663. doi: 10.3390/v14081663.
Vaccination coverage against COVID-19 among health care workers (HCWs) of the University Health Agency Giuliano-Isontina (ASUGI) of Trieste (North-eastern Italy) by 1 January 2022 was 90.4% with at least one vaccine dose, 84.9% with at least 2 doses, and 75.1% with 3 doses, 98.2% with Comirnaty (Pfizer BioNtech, New York, NY, USA) versus 1.8% with Spikevax (Moderna, Cambridge, MA, USA). From 1 October 2020 to 7 February 2022, 1652 SARS-CoV-2 infections were notified in HCWs of ASUGI Trieste. Although the overall risk of SARS-CoV-2 contagion increased over time, the rate of occupational infections progressively declined, from 42.5% during the second COVID-19 wave to 15.6% in the fifth. Between 1 January-7 February 2022 (a period dominated by the Omicron variant), albeit no COVID-19-associated hospitalizations were recorded in HCWs of ASUGI Trieste, 669 SARS-CoV-2 infections were counted against 367 cases observed from 1 October to 31 December 2020, the 3 months preceding the implementation of the vaccination campaign against COVID-19. Job tasks and health care settings turned out to be the most significant risk factors for SARS-CoV-2 infection. However, the effect of workplace prevailed over job task on the biological risk, with greater rates of SARS-CoV-2 infections observed among HCWs operating in areas with higher levels of circulation of the virus, particularly COVID-19 dedicated units.
2022 年 1 月 1 日，的里雅斯特（意大利东北部）朱利亚诺-伊斯蒂诺大学卫生机构（ASUGI）卫生保健工作者（HCWs）接种 COVID-19 疫苗的覆盖率为 90.4%，至少接种了一剂疫苗，84.9%至少接种了两剂，75.1%接种了三剂，98.2%接种了 Comirnaty（辉瑞生物科技，纽约，NY，美国），而 1.8%接种了 Spikevax（莫德纳，剑桥，MA，美国）。从 2020 年 10 月 1 日至 2022 年 2 月 7 日，ASUGI 通知了 1652 例 SARS-CoV-2 感染。尽管 SARS-CoV-2 感染的总体风险随时间推移而增加，但职业感染率逐渐下降，从第二波 COVID-19 期间的 42.5%降至第五波的 15.6%。2022 年 1 月 1 日至 2 月 7 日期间（主要受奥密克戎变异株影响），尽管 ASUGI 的 HCWs 没有 COVID-19 相关住院记录，但记录了 669 例 SARS-CoV-2 感染，而在 COVID-19 疫苗接种运动实施前的 3 个月（即 2020 年 10 月至 12 月 31 日）观察到了 367 例。工作任务和医疗保健环境是 SARS-CoV-2 感染的最重要危险因素。然而，工作场所对生物风险的影响超过了工作任务，在病毒传播水平较高的地区工作的 HCWs 感染 SARS-CoV-2 的比例更高，特别是 COVID-19 专用单位。
