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大麻合法化前后儿童的意外大麻暴露:来自一家加拿大儿童医院的回顾性研究。

Unintentional cannabis exposures in children pre- and post-legalization: A retrospective review from a Canadian paediatric hospital.

作者信息

Coret Alon, Rowan-Legg Anne

机构信息

Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

Paediatr Child Health. 2022 Jun 22;27(5):265-271. doi: 10.1093/pch/pxab090. eCollection 2022 Sep.

Abstract

OBJECTIVES

Canada legalized recreational cannabis in October 2018. Cannabis is increasingly available in numerous forms-especially edibles-that make children vulnerable to unintentional intoxication. We sought to: determine the frequency of visits due to cannabis intoxication pre- and post-legalization; characterize the clinical features and circumstances of cannabis intoxication in the paediatric population; and create greater awareness among healthcare providers about this issue.

METHODS

We performed a retrospective chart review of Emergency Department visits at the Children's Hospital of Eastern Ontario (Ottawa, ON) between March 2013 and September 2020. Inclusion criteria were: age <18 years; unintentional cannabis ingestion, identified by ICD-10 codes T40.7 and X42. We assessed basic demographics, clinical signs and symptoms, exposure details, investigations, and patient disposition.

RESULTS

A total of 37 patients (22 male) met inclusion criteria, mean age 5.9±3.8 years. Most visits (32; 86%) occurred in the 2-year period after legalization. Altered levels of consciousness, lethargy/somnolence, tachycardia, and vomiting were the most common presenting signs and symptoms. The majority of exposures were to edibles (28; 76%) in the home setting (30; 81%). Poison control and child protective services were involved in 19 (51%) and 22 (59%) of cases, respectively. Twelve patients (32%) required admission to the hospital, the majority of whom stayed <24 h.

CONCLUSIONS

Our data confirm increased paediatric hospital visits related to unintentional cannabis exposures post-legalization. Consideration of this clinical presentation is critical for acute care providers. Advocacy for safe storage strategies and appropriate enforcement of marketing/packaging legislation are imperative for public health policymakers.

摘要

目的

2018年10月加拿大将休闲用大麻合法化。大麻有多种形式可供获取,尤其是食用大麻制品,这使得儿童容易意外中毒。我们旨在:确定大麻合法化前后因大麻中毒而就诊的频率;描述儿科人群大麻中毒的临床特征和情况;提高医疗服务提供者对该问题的认识。

方法

我们对2013年3月至2020年9月期间安大略东部儿童医院(渥太华,安大略省)急诊科的就诊情况进行了回顾性图表审查。纳入标准为:年龄<18岁;通过ICD-10编码T40.7和X42确定为意外摄入大麻。我们评估了基本人口统计学信息、临床体征和症状、接触细节、检查以及患者处置情况。

结果

共有37名患者(22名男性)符合纳入标准,平均年龄5.9±3.8岁。大多数就诊(32例;86%)发生在合法化后的两年内。意识水平改变、嗜睡/昏睡、心动过速和呕吐是最常见的症状和体征。大多数接触是在家中接触食用大麻制品(28例;76%)(30例;81%)。分别有19例(51%)和22例(59%)涉及中毒控制中心和儿童保护服务机构。12名患者(32%)需要住院治疗,其中大多数住院时间<24小时。

结论

我们的数据证实,大麻合法化后与意外接触大麻相关的儿科医院就诊有所增加。对于急性护理提供者来说,考虑这种临床表现至关重要。倡导安全储存策略以及适当执行营销/包装立法对公共卫生政策制定者来说势在必行。

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