Kojima Sho, Morishita Shinichiro, Hotta Kazuki, Qin Weixiang, Usui Naoto, Tsubaki Atsuhiro
Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan.
Department of Physical Therapy, Kisen Hospital, Tokyo, Japan.
Front Physiol. 2022 Aug 9;13:794473. doi: 10.3389/fphys.2022.794473. eCollection 2022.
A recent study has reported that prefrontal cortex (PFC) activity during incremental exercise may be related to exercise termination on exhaustion. However, few studies have focused on motor-related areas during incremental exercise. This study investigated changes in the oxygenation of the PFC and motor-related areas using near-infrared spectroscopy during incremental exercise. Moreover, we analyzed the effect of exercise termination on changes in cortical oxygenation based on exercise intensity and respiratory metabolism. Sixteen healthy young male patients participated in this study. After a 4-min rest and 4-min warm-up period, incremental exercise was started at an incremental load corresponding to 20 W/min. Oxyhemoglobin (OHb), deoxyhemoglobin (HHb), and total hemoglobin (THb) in the bilateral PFC, supplementary motor area, and primary motor cortex were measured. We evaluated changes in oxygenation in each cortex before and after the anaerobic threshold (AT) and respiratory compensation point to identify changes due to respiratory metabolism. OHb and THb increased from moderate intensity or after AT to maximal exercise, and HHb increased slowly compared to OHb and THb; these changes in hemoglobin levels were consistent in all cortical areas we measured. However, the increase in each hemoglobin level in the bilateral PFC during incremental exercise was faster than that in motor-related areas. Moreover, changes in cortical oxygenation in the right PFC were faster than those in the left PFC. These results suggest changes based on differences in neural activity due to the cortical area.
最近一项研究报告称，递增运动期间前额叶皮质（PFC）的活动可能与运动至疲惫时的运动终止有关。然而，很少有研究关注递增运动期间与运动相关的区域。本研究使用近红外光谱法调查了递增运动期间PFC和与运动相关区域的氧合变化。此外，我们基于运动强度和呼吸代谢分析了运动终止对皮质氧合变化的影响。16名健康年轻男性患者参与了本研究。在4分钟休息和4分钟热身期后，以对应20W/分钟的递增负荷开始递增运动。测量双侧PFC、辅助运动区和初级运动皮层中的氧合血红蛋白（OHb）、脱氧血红蛋白（HHb）和总血红蛋白（THb）。我们评估了无氧阈（AT）和呼吸补偿点前后每个皮层的氧合变化，以确定由于呼吸代谢引起的变化。OHb和THb从中等强度或AT后至最大运动时增加，与OHb和THb相比，HHb增加缓慢；我们测量的所有皮层区域中血红蛋白水平的这些变化是一致的。然而，递增运动期间双侧PFC中每种血红蛋白水平的增加比与运动相关区域更快。此外，右侧PFC中皮质氧合的变化比左侧PFC更快。这些结果表明，基于皮质区域神经活动差异存在变化。
