Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India.
Department of Periodontology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, India.
J Long Term Eff Med Implants. 2022;32(4):83-94. doi: 10.1615/JLongTermEffMedImplants.2022043121.
Understanding the microbiological makeup of peri-implant biofilm could contribute to the discovery of focused treatment strategies, improving the outcome of peri-implantitis management. However, the bacterial profile in diseased periodontal and peri-implant sulci is still unclear. This systematic review aims to analyze the microbiological similarities and differences between diseased periodontal and peri-implant sulci based on the available literature evidence. A thorough search was conducted in electronic databases such as PubMed, Google Scholar, and Cochrane, as well as a manual search employing the eligibility criteria. After a thorough review, studies evaluating the microbial composition acquired from plaque samples obtained from patients with diseased periodontal and peri-implant sulci were chosen. The selected 8 studies evaluated the differences in microbial profile in periodontitis and peri-implantitis. Five studies found a statistically significant variation in the microbial profile between diseased periodontal and peri-implant sulci, while in one study, no changes in the microbiology of inflammatory peri-implant and periodontal sites were observed. In one of the two in situ studies, the structure of the transcription level and core species was different in peri-implantitis, whereas the other in situ study found that the 16S rRNA-based bacterial profile of both the diseases were different, while the functional genes, taxonomic, and virulence factor mRNA profiles were identical. According to existing studies, significant differences in the biofilm composition of diseased periodontal and peri-implant sulci were observed. Therefore, periodontitis and peri-implantitis have diverse microbial characteristics.
了解种植体周围生物膜的微生物组成可能有助于发现有针对性的治疗策略，从而改善种植体周围炎的管理效果。然而，患病牙周袋和种植体周围沟的细菌特征仍不清楚。本系统评价旨在根据现有文献证据，分析患病牙周袋和种植体周围沟的微生物相似性和差异性。我们在电子数据库（如 PubMed、Google Scholar 和 Cochrane）中进行了全面检索，并采用纳入标准进行了手动检索。经过仔细审查，选择了评估从患有牙周病和种植体周围炎患者的菌斑样本中获得的微生物组成的研究。选择的 8 项研究评估了牙周炎和种植体周围炎之间微生物特征的差异。五项研究发现，患病牙周袋和种植体周围沟的微生物特征存在统计学显著差异，而一项研究则观察到炎症性种植体周围和牙周部位的微生物学没有变化。在两项原位研究中，一项研究发现种植体周围炎的转录水平和核心物种结构不同，而另一项研究则发现两种疾病的 16S rRNA 基于的细菌特征不同，而功能基因、分类和毒力因子 mRNA 特征则相同。根据现有研究，患病牙周袋和种植体周围沟的生物膜组成存在显著差异。因此，牙周炎和种植体周围炎具有不同的微生物特征。
