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[尿液中他林洛尔(可旦胺)的薄层分析——一种监测高血压患者药物依从性的筛查方法]

[Thin layer analysis of talinolol (Cordanum) in urine--a screening method for monitoring of drug compliance in hypertensive patients].

作者信息

Vogel I, Rostock G, Günzel R, Faulhaber H D

出版信息

Pharmazie. 1987 Mar;42(3):165-6.

PMID:3602071
Abstract

A simple and rapid analytical method for TLC detection of talinolol (Cordanum) is described. Because of its low technical expense it can be used for routine application in clinical laboratories. Triamteren (substance of contents of Triampur comp.) is detected simultaneously. This method has till now been applied to urine specimens of 145 hypertensive patients taking talinolol (n = 95) and triamteren (n = 50). The spectrofluorimetric analysis of talinolol was used as a reference method (r = 0.95).

摘要

描述了一种用于薄层色谱法检测他林洛尔(Cordanum)的简单快速分析方法。由于其技术成本低,可用于临床实验室的常规应用。同时检测氨苯蝶啶(Triampur comp.的成分物质)。该方法迄今已应用于145例服用他林洛尔(n = 95)和氨苯蝶啶(n = 50)的高血压患者的尿液标本。他林洛尔的荧光分光光度分析用作参考方法(r = 0.95)。

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