• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[科林法缓释片单药治疗以及与可多纳和曲安普明联合治疗高血压患者的药代动力学研究]

[A pharmacokinetic study of korinfar-retard in monotherapy and in combination with cordanum and triampur in patients with arterial hypertension].

作者信息

Kukes V G, Ignat'ev V I, Kurapov A P, Pavlov S S, Rumiantsev A S, Chil'tsov V V

出版信息

Eksp Klin Farmakol. 1994 Nov-Dec;57(6):50-2.

PMID:7756964
Abstract

The long-acting corinfar formulation, corinfar-retard tablets, 20 mg (AWD, Germany), was studied for pharmacokinetics in single and course use in 40 patients with arterial hypertension, as well as for its effects of cordanum and triampur. Patients' plasma corinfar was measured by high performance liquid chromatography. There were no changes in the pharmacokinetics of the agent when it was used in its course use. Cordanum and triampur was demonstrated to have no effects on the pharmacokinetics of corinfar during their application.

摘要

对长效科利法尔制剂(科利法尔缓释片,20毫克,德国AWD公司生产)在40例动脉高血压患者单次及疗程使用时的药代动力学进行了研究,并研究了其与可多拿和曲安西龙的相互作用。采用高效液相色谱法测定患者血浆中的科利法尔含量。该药物在疗程使用时药代动力学无变化。研究表明,可多拿和曲安西龙在应用过程中对科利法尔的药代动力学无影响。

相似文献

1
[A pharmacokinetic study of korinfar-retard in monotherapy and in combination with cordanum and triampur in patients with arterial hypertension].[科林法缓释片单药治疗以及与可多纳和曲安普明联合治疗高血压患者的药代动力学研究]
Eksp Klin Farmakol. 1994 Nov-Dec;57(6):50-2.
2
[The pharmacokinetics of different drug forms of nifedipine when used singly and in a course as monotherapy and in combination with Cordanum and triampur preparations in patients with arterial hypertension].
Eksp Klin Farmakol. 1995 Nov-Dec;58(6):22-5.
3
[The clinical efficacy of Korinfar-retard in combination with Cordanum, triampur and Capoten in patients with arterial hypertension].科瑞法缓释片联合可多拿、曲帕胺和开博通治疗动脉高血压患者的临床疗效
Klin Med (Mosk). 1996;74(2):20-3.
4
[Relation between the hypotensive effect of triampur and its pharmacokinetics in patients with hypertension].[曲安西龙在高血压患者中的降压作用与其药代动力学之间的关系]
Kardiologiia. 1986 Mar;26(3):49-52.
5
[The use of the delayed-action form of korinfar in arterial hypertension, stenocardia and hypertrophic cardiomyopathy].[korinfar延迟作用剂型在动脉高血压、心绞痛和肥厚型心肌病中的应用]
Ter Arkh. 1996;68(1):39-42.
6
[Therapy of essential hypertension using a new beta-receptor blockader (timolol maleate) combined with hydrochlorothiazide].使用新型β受体阻滞剂(马来酸噻吗洛尔)联合氢氯噻嗪治疗原发性高血压
Verh Dtsch Ges Inn Med. 1974;80:272-4.
7
[The use of Cordanum in combination with Corinfar-Retard for the treatment of ectopic arrhythmias in the sick sinus syndrome in patients with ischemic heart disease].[可多胺与缓释可立复联合用于治疗缺血性心脏病患者病态窦房结综合征中的异位心律失常]
Ter Arkh. 1997;69(9):59-61.
8
[Hypotensive effect of hydrochlorothiazide and its combination with triamterene].
Sov Med. 1989(6):5-8.
9
Factorial antihypertensive study of an extended-release metoprolol and hydrochlorothiazide combination.美托洛尔缓释片与氢氯噻嗪联合使用的析因降压研究
Am J Hypertens. 2006 Dec;19(12):1217-25. doi: 10.1016/j.amjhyper.2006.05.007.
10
A randomised crossover comparison of reserpine and sustained-release nifedipine in hypertension.利血平和缓释硝苯地平治疗高血压的随机交叉对照研究
Cent Afr J Med. 1997 Dec;43(12):344-9.