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青年人群暴露前预防(PrEP)污名量表的编制与验证。

Development and Validation of the Youth Pre-Exposure Prophylaxis (PrEP) Stigma Scale.

机构信息

Center of Population Sciences for Health Equity, College of Nursing, Florida State University, 32306, Tallahassee, FL, USA.

Department of Psychology, Faculty of Arts and Sciences, TED University, Ankara, Turkey.

出版信息

AIDS Behav. 2023 Mar;27(3):929-938. doi: 10.1007/s10461-022-03829-9. Epub 2022 Aug 27.

DOI:10.1007/s10461-022-03829-9
PMID:36029425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9968821/
Abstract

To date, there are no established scales to assess PrEP stigma among youth. We validated the Youth PrEP Stigma Scale within the Adolescent Trials Network P3 study (2019-2021). Data from sexual and gender minority youth (16-24 years) who were prescribed PrEP across nine domestic sites were evaluated (N = 235). Descriptive statistics, exploratory factor analysis, and correlation coefficients are reported. Results yielded a three-factor solution (PrEP Disapproval by Others, Enacted PrEP Stigma, and PrEP User Stereotypes) with strong factor loadings and Cronbach's alphas ranging from 0.83 to 0.90, suggesting excellent internal consistency. Correlations between this Scale, anticipated HIV stigma, perceived HIV risk, and disclosure of sexual identity were significant, indicating potential for robust application. Given the persistence of HIV infections among youth, stigma as a barrier to prevention, and expansion of PrEP modalities, the Youth PrEP Stigma Scale could enhance intervention and mechanistic research among youth at elevated risk for HIV acquisition.

摘要

迄今为止,尚无评估青年中 PrEP 污名的既定量表。我们在青少年试验网络 P3 研究(2019-2021 年)中验证了青年 PrEP 污名量表。对在九个国内地点接受 PrEP 处方的性和性别少数青年(16-24 岁)的数据进行了评估(N=235)。报告了描述性统计数据、探索性因素分析和相关系数。结果得出了一个三因素解决方案(他人对 PrEP 的不赞成、实施的 PrEP 污名和 PrEP 用户刻板印象),具有很强的因子负荷和 0.83 至 0.90 的 Cronbach's α,表明具有极好的内部一致性。该量表与预期的 HIV 污名、感知的 HIV 风险以及性身份的披露之间的相关性具有统计学意义,表明其具有很强的应用潜力。鉴于青年中 HIV 感染的持续存在、污名是预防的障碍以及 PrEP 方式的扩展,青年 PrEP 污名量表可以加强针对 HIV 感染风险较高的青年的干预和机制研究。

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