College of Nursing, Florida State University, Tallahassee, FL, USA.
Institute on Digital Health and Innovation, College of Nursing, Florida State University, Tallahassee, FL, 32306, USA.
BMC Public Health. 2024 Sep 10;24(1):2469. doi: 10.1186/s12889-024-19868-x.
BACKGROUND: Few validated brief scales are available to measure constructs that may hinder mpox-related prevention and care engagement, such as knowledge and stigma. Both are highly salient barriers to infectious disease care and disease understanding, precursors to evaluating one's risk and need to, for example, accept vaccination. To address this gap, we developed and validated the Mpox Stigma Scale (MSS) and Mpox Knowledge Scale (MKS). METHODS: As part of a full-scale clinical trial, we offered an optional mpox survey to participants who self-identified as African American or Black, were 18-29 years old, and lived in Alabama, Georgia, or North Carolina (2023, N = 330). We calculated psychometric properties through confirmatory factor analyses (CFA) and applied Comparative Fit Index (CFI), Goodness of Fit Index (GFI), and Tucker-Lewis Index (TLI) values equal to or exceeding 0.90 and Root Mean Square Error of Approximation (RMSEA) and Standardized Root Mean Square Residual (SRMR) values less than 0.08 to determine adequate model fit. We computed internal reliability using Cronbach's alpha and calculated Pearson or Spearman correlation coefficients between the MSS and MKS and related variables. RESULTS: For the MSS, CFA results showed that the one-factor model fit the data well (χ(df = 5, N = 330) = 34.962, CFI = 0.97, GFI = 0.99, TLI = 0.94, RMSEA = 0.13, SRMR = 0.03). For the MKS, the one-factor model provided a good fit to the data (χ(df = 6, N = 330) = 8.44, CFI = 0.99, GFI = 0.99, TLI = 0.95, RMSEA = 0.15, SRMR = 0.02). Cronbach's alphas were MSS = 0.91 and MKS = 0.83, suggesting good to excellent reliability. The MSS was correlated with the MKS (r = .55, p < .001), stigmatizing attitudes (r = .24, p < .001), attitudes towards mpox vaccination (r=-.12, p = .030), and worry about contracting mpox (r = .44, p < .001). The MKS was correlated with worry about contracting mpox (r = .30, p < .001) and mpox disclosure (r=-.16, p = .003). CONCLUSIONS: The MSS and MKS are reliable and valid tools for public health practice, treatment and prevention research, and behavioral science. Further validation is warranted across populations and geographic locations. TRIAL REGISTRATION: ClinicalTrials.gov NCT05490329.
背景：目前可用的简短量表很少，无法衡量可能阻碍猴痘相关预防和护理参与的因素，例如知识和耻辱感。这两者都是传染病护理和疾病理解的高度突出障碍，是评估一个人风险和接受疫苗接种等需求的前兆。为了解决这一差距，我们开发并验证了猴痘耻辱量表 (MSS) 和猴痘知识量表 (MKS)。
方法：作为一项全面临床试验的一部分，我们向自我认定为非裔美国人或黑人、年龄在 18-29 岁之间、居住在阿拉巴马州、佐治亚州或北卡罗来纳州的参与者提供了一项可选的猴痘调查 (2023 年，N=330)。我们通过验证性因素分析 (CFA) 计算心理测量学特性，并应用比较拟合指数 (CFI)、良好拟合指数 (GFI) 和塔克-刘易斯指数 (TLI) 值等于或超过 0.90 以及均方根误差逼近 (RMSEA) 和标准化均方根残差 (SRMR) 值小于 0.08 来确定适当的模型拟合度。我们使用 Cronbach 的 alpha 计算内部可靠性，并计算 MSS 和 MKS 与相关变量之间的 Pearson 或 Spearman 相关系数。
结果：对于 MSS，CFA 结果表明单因素模型很好地拟合了数据 (χ(df=5，N=330)=34.962，CFI=0.97，GFI=0.99，TLI=0.94，RMSEA=0.13，SRMR=0.03)。对于 MKS，单因素模型提供了对数据的良好拟合 (χ(df=6，N=330)=8.44，CFI=0.99，GFI=0.99，TLI=0.95，RMSEA=0.15，SRMR=0.02)。Cronbach 的 alpha 为 MSS=0.91 和 MKS=0.83，表明可靠性良好至优秀。MSS 与 MKS 相关 (r=0.55，p<0.001)、耻辱感态度 (r=0.24，p<0.001)、对猴痘疫苗接种的态度 (r=-.12，p=0.030) 和对感染猴痘的担忧 (r=0.44，p<0.001)。MKS 与对感染猴痘的担忧 (r=0.30，p<0.001) 和猴痘披露 (r=-.16，p=0.003) 相关。
结论：MSS 和 MKS 是公共卫生实践、治疗和预防研究以及行为科学的可靠有效的工具。需要在不同人群和地理位置进一步验证。
试验注册：ClinicalTrials.gov NCT05490329。
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