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孕早期新型冠状病毒肺炎感染患者合并先天性心脏病:一例报告

Congenital heart disease in a patient with COVID-19 infection during early pregnancy: a case report.

作者信息

Abdelkader Mohamed Ali, Abbas Hamed Mohamed, Aboelkhair Ibrahim Mohamed, Alafify Aliaa Salah Ali, Elgazzar Basim Abdelfattah, Koura Mai Salah El-Din

机构信息

Fetal Medicine Unit, Cairo University, Cairo, Egypt.

Menoufia University, El-Menoufia, Egypt.

出版信息

Egypt Heart J. 2022 Aug 27;74(1):61. doi: 10.1186/s43044-022-00295-5.

Abstract

BACKGROUND

Since the end of 2019, the world has been afflicted by a coronavirus pandemic caused by coronavirus 2 (severe acute respiratory syndrome) (SARS-CoV-2). COVID-19 causes a wide range of signs and symptoms with varying consequences. The impact of the COVID-19 infection on pregnant women and their fetuses is still under investigation.

CASE PRESENTATION

A case of a 34-years-old non-vaccinated pregnant woman who had a COVID-19 infection in the first month of her pregnancy and went into premature labor at 34 weeks was reported. Congenital heart disease and hydrops were present in the fetus. The infant girl was cyanotic after delivery, experienced bradycardia, and was in poor overall condition; she was admitted to the NICU and died 5 days later.

CONCLUSIONS

Some theories suggest that SARS-CoV-2 may be transmitted vertically from mother to fetus. Congenital abnormalities can be caused by a variety of viruses. Although, congenital heart diseases can occur due to different causes, we suggest that COVID-19 may play a role in the development of congenital heart defects.

摘要

背景

自2019年底以来,世界一直受到由冠状病毒2(严重急性呼吸综合征)(SARS-CoV-2)引起的冠状病毒大流行的困扰。COVID-19会引发各种体征和症状,后果各不相同。COVID-19感染对孕妇及其胎儿的影响仍在研究中。

病例报告

报告了一例34岁未接种疫苗的孕妇,她在怀孕第一个月感染了COVID-19,并在34周时早产。胎儿患有先天性心脏病和水肿。女婴出生后脸色发青,出现心动过缓,总体状况不佳;她被送入新生儿重症监护病房,5天后死亡。

结论

一些理论表明,SARS-CoV-2可能会从母亲垂直传播给胎儿。多种病毒可导致先天性异常。虽然先天性心脏病可由不同原因引起,但我们认为COVID-19可能在先天性心脏缺陷的发生中起作用。

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