Wang Rong-Yue, Zheng Ke-Qiong, Xu Bo-Zhong, Zhang Wei, Si Jin-Ge, Xu Chong-Yong, Chen Hua, Xu Zhang-Ye, Wu Xin-Mei
Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Department of Obstetrics and Gynecology, The Yueqing People's Hospital, Wenzhou 325600, Zhejiang Province, China.
World J Clin Cases. 2020 Dec 6;8(23):6016-6025. doi: 10.12998/wjcc.v8.i23.6016.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered coronavirus that has generated a worldwide outbreak of infections. Many people with coronavirus disease-2019 (COVID-19) have developed severe illness, and a significant number have died. However, little is known regarding infection by the novel virus in pregnant women. We herein present a case of COVID-19 confirmed in a woman delivering a neonate who was negative for SARS-CoV-2 and related it to a review of the literature on pregnant women and human coronavirus infections.
The patient was a 36-year-old pregnant woman in her third trimester who had developed progressive clinical symptoms when she was confirmed as infected with SARS-CoV-2. Given the potential risks for both the pregnant woman and the fetus, an emergency cesarean section was performed, and the baby and his mother were separately quarantined and cared for. As a result, the baby currently shows no signs of SARS-CoV-2 infection (his lower respiratory tract samples were negative for the virus), while the mother completely recovered from COVID-19.
Although we presented a single case, the successful result is of great significance for pregnant women with SARS-CoV-2 infection and with respect to fully understanding novel coronavirus pneumonia.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是一种新发现的冠状病毒,已在全球引发感染疫情。许多2019冠状病毒病(COVID-19)患者病情严重,大量患者死亡。然而,关于这种新型病毒在孕妇中的感染情况知之甚少。我们在此报告一例在分娩新生儿时确诊为COVID-19的病例,该新生儿SARS-CoV-2检测呈阴性,并结合对孕妇及人类冠状病毒感染相关文献的回顾进行阐述。
患者为一名36岁孕晚期孕妇,确诊感染SARS-CoV-2后出现进行性临床症状。鉴于对孕妇和胎儿均存在潜在风险,遂行急诊剖宫产,婴儿及其母亲被分别隔离并接受护理。结果,婴儿目前未显示出SARS-CoV-2感染迹象(其下呼吸道样本病毒检测呈阴性),而母亲已从COVID-19中完全康复。
尽管我们仅报告了一例病例,但这一成功结果对于感染SARS-CoV-2的孕妇以及全面了解新型冠状病毒肺炎具有重要意义。