采用曲美替尼治疗的伴有新型CUX1-BRAF融合突变的巨大先天性黑素细胞痣 - Suppr

Giant congenital melanocytic naevus with a novel CUX1-BRAF fusion mutation treated with trametinib.

作者信息

Molho-Pessach Vered, Hartshtark Stav, Merims Sharon, Lotem Michal, Caplan Nadia, Alfassi Hila, Maly Alex, Goldstein Gal, Muskatel Rakefet Sidlik

机构信息

Departments of Dermatology, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel.

Oncology, Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel.

出版信息

Br J Dermatol. 2022 Dec;187(6):1052-1054. doi: 10.1111/bjd.21851. Epub 2022 Sep 16.

DOI:10.1111/bjd.21851

PMID:36030465

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10087742/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e3d/10087742/633bc9e33cbe/BJD-187-1052-g001.jpg

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Giant congenital melanocytic naevus with a novel CUX1-BRAF fusion mutation treated with trametinib.采用曲美替尼治疗的伴有新型CUX1-BRAF融合突变的巨大先天性黑素细胞痣

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Novel genetic alteration in congenital melanocytic nevus: MAP2K1 germline mutation with BRAF somatic mutation.先天性黑色素细胞痣中的新的遗传改变：MAP2K1 种系突变伴 BRAF 体细胞突变。

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Giant Congenital Melanocytic Nevus Treated With Trametinib.巨先天性黑色素细胞痣用曲美替尼治疗。

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Giant congenital melanocytic naevus with a novel CUX1-BRAF fusion mutation treated with trametinib.

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