School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.
Beijing Center for Physical and Chemical Analysis, Beijing 100089, China.
Genomics Proteomics Bioinformatics. 2023 Feb;21(1):97-107. doi: 10.1016/j.gpb.2022.07.007. Epub 2022 Aug 27.
Recent advances in next-generation sequencing technologies and improvements in bioinformatics have expanded the scope of microbiome analysis as a forensic tool. Microbiome research is concerned with the study of the compositional profile and diversity of microbial flora as well as the interactions between microbes, hosts, and the environment. It has opened up many new possibilities for forensic analysis. In this review, we discuss various applications of microbiome in forensics, including identification of individuals, geolocation inference, and post-mortem interval (PMI) estimation.
近年来，下一代测序技术的进步和生物信息学的改进扩展了微生物组分析作为法庭工具的范围。微生物组研究关注微生物群落的组成谱和多样性以及微生物、宿主和环境之间的相互作用。它为法医分析开辟了许多新的可能性。在这篇综述中，我们讨论了微生物组在法医学中的各种应用，包括个体识别、地理位置推断和死后间隔（PMI）估计。
