Department of Physiotherapy and Occupational Therapy, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 29, Level 8, 3. Floor, O1, 2730 Herlev, Denmark.
Department of Physiotherapy and Occupational Therapy, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 29, Level 8, 3. Floor, O1, 2730 Herlev, Denmark; Hospital Secretariat and Communication, Research, Copenhagen University Hospital, Herlev and Gentofte, 2730 Herlev, Denmark.
Crit Rev Oncol Hematol. 2022 Oct;178:103802. doi: 10.1016/j.critrevonc.2022.103802. Epub 2022 Aug 27.
Effects of exercise in patients with breast cancer have been thoroughly investigated. The aim was to explore differences in effects regarding type, delivery mode and extensiveness (e.g. intensity; volume) of the interventions.
We searched for randomised controlled trials including patients with breast cancer receiving systemic treatment, exercise-based interventions, and measures on patient reported- and objectively measured outcomes.
Exercise showed significant and moderate effects on the primary outcomes quality of life and physical function, Standardised Mean Difference: 0.52 (95 % CI 0.38-0.65) and 0.52 (95 % CI 0.38-0.66), respectively. Type of exercise had little influence on the effects, however combined aerobic- and resistance exercise seemed superior for increasing physical function, compared to aerobic or resistance exercise. Supervised interventions were superior to partly and unsupervised. Extensiveness of the intervention only influenced physical function.
Supervised interventions, more than type or extensiveness of interventions, seem to increase effects.
运动对乳腺癌患者的影响已经得到了深入研究。本研究旨在探讨不同类型、实施方式和强度(如强度;量)的干预措施对效果的影响。
我们检索了纳入接受系统治疗的乳腺癌患者、基于运动的干预措施以及患者报告和客观测量结果的随机对照试验。
运动对生活质量和身体功能这两个主要结局指标具有显著的中等影响,标准化均数差分别为 0.52(95%置信区间 0.38-0.65)和 0.52(95%置信区间 0.38-0.66)。运动类型对效果影响不大,但与单纯有氧或抗阻运动相比,有氧和抗阻联合运动似乎更能提高身体功能。监督干预优于部分监督和非监督干预。干预的广度仅影响身体功能。
监督干预,而不是干预的类型或强度,似乎更能增加效果。