Kümin Daniel, Albert Monika Gsell, Weber Benjamin, Summermatter Kathrin
Lonza, Visp, Switzerland.
Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Appl Biosaf. 2020 Dec 1;25(4):214-224. doi: 10.1177/1535676020921007.
When working with pathogens in laboratories, animal or production facilities, and even hospitals, the potential need for room fumigation for decontamination purposes must be taken into consideration. Questions regarding the choice of fumigant, technical aspects of the room, its ventilation, the fumigation system to be used, and other issues will arise and will have to be addressed.
This article is based on literature searches and was compiled using the authors' long-time personal experience in room and filter fumigation using various fumigation systems.
The article can be used as a guide to establish an effective fumigation system in a laboratory or an animal facility setting and may be adapted for use in hospitals. Different systems for hydrogen peroxide fumigation on the market are presented. Also, technical aspects are discussed.
Hydrogen peroxide is used in various forms for fumigation of rooms, equipment, and filters. Regardless of the individual limitations of these forms, hydrogen peroxide is a versatile fumigation method. However, it is important to consider numerous technical requirements when planning to implement hydrogen peroxide fumigation at an institution.
Subsequent to the present overview of different fumigation systems based on hydrogen peroxide on the market and their technical requirements, part 2 of this article will focus on validation and verification of hydrogen peroxide fumigation while considering the entire fumigation process. The two parts together will serve users as a guide to establishing hydrogen peroxide fumigations at their facilities.
在实验室、动物或生产设施甚至医院中处理病原体时，必须考虑出于去污目的对房间进行熏蒸消毒的潜在需求。关于熏蒸剂的选择、房间的技术方面、通风情况、要使用的熏蒸系统以及其他问题将会出现，必须加以解决。
本文基于文献检索，并结合作者在使用各种熏蒸系统进行房间和过滤器熏蒸消毒方面的长期个人经验编写而成。
本文可作为在实验室或动物设施环境中建立有效熏蒸系统的指南，并可适用于医院。介绍了市场上不同的过氧化氢熏蒸系统。还讨论了技术方面的问题。
过氧化氢以各种形式用于房间、设备和过滤器的熏蒸消毒。尽管这些形式存在各自的局限性，但过氧化氢是一种通用的熏蒸方法。然而，在机构计划实施过氧化氢熏蒸消毒时，考虑众多技术要求非常重要。
在对市场上基于过氧化氢的不同熏蒸系统及其技术要求进行本次概述之后，本文的第2部分将聚焦于过氧化氢熏蒸消毒的验证和核查，同时考虑整个熏蒸过程。这两部分内容将共同为用户在其设施中建立过氧化氢熏蒸消毒提供指南。
