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肝移植与布加综合征:病因如何成为解决方案。

Liver Transplantation and Budd-Chiari Syndrome: When the Cause Becomes the Solution.

作者信息

Garmpis Nikolaos, Damaskos Christos, Prevezanos Dionysios, Garmpi Anna, Georgakopoulou Vasiliki E, Antoniou Efstathios A, Kouraklis Gregory, Dimitroulis Dimitrios

机构信息

Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Maedica (Bucur). 2022 Jun;17(2):415-419. doi: 10.26574/maedica.2022.17.2.415.

Abstract

Budd-Chiari syndrome consists a rare medical entity which has an estimated incidence of 0.1 to 10 people per million every year. It is defined by the obstruction of the flow in the inferior vena cava or the hepatic veins. Various classifications have been proposed. So, it can be acute or chronic and primary or secondary. Iatrogenic, a subtype of secondary Budd-Chiari syndrome, is caused by various medical interventions, including liver transplantation. On the other hand, liver transplantation is the ultimate therapeutic management of Budd-Chiari syndrome. Finally, a medical paradox and a vicious circle has been created. Liver transplantation can potentially be both the cause and treatment of Budd-Chiari syndrome. Budd-Chiari syndrome is simultaneously the cause and complication of liver transplantation. Our aim is to describe this double role of liver transplantation in Budd-Chiari syndrome and to acknowledge that a high degree of clinical suspicion is necessary for the proper recognition and management of this life-threatening condition.

摘要

布加综合征是一种罕见的医学病症,估计每年每百万人中有0.1至10人发病。它是由下腔静脉或肝静脉血流受阻所定义的。已经提出了各种分类方法。因此,它可以是急性或慢性的,原发性或继发性的。医源性布加综合征是继发性布加综合征的一种亚型,由包括肝移植在内的各种医疗干预引起。另一方面,肝移植是布加综合征的最终治疗手段。最后,形成了一个医学上的悖论和恶性循环。肝移植可能既是布加综合征的病因又是其治疗方法。布加综合征同时是肝移植的病因和并发症。我们的目的是描述肝移植在布加综合征中的这种双重作用,并认识到对于正确识别和处理这种危及生命的病症,高度的临床怀疑是必要的。

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