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种族差异与青光眼:从流行病学到病理生理学。

Racial Disparities in Glaucoma: From Epidemiology to Pathophysiology.

机构信息

John F. Hardesty MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri.

出版信息

Mo Med. 2022 Jan-Feb;119(1):49-54.

Abstract

Among individuals of African and Latinx descent compared to those of European background, there is a higher prevalence, earlier onset, more rapid progression of primary open angle glaucoma and greater incidence of blindness. Although some suggest that outreach, education and screening programs may expand earlier diagnosis, and attention to access, cost of treatment, and adherence will improve outcomes, there is increasing evidence of genetic and physiologic differences which may be associated with these disease disparities.

摘要

与欧洲背景的人相比,非洲裔和拉丁裔个体原发性开角型青光眼的患病率更高、发病更早、进展更快,失明的发生率也更高。尽管有人认为外展、教育和筛查计划可能会扩大早期诊断的范围,而对获得途径、治疗费用和依从性的关注将改善治疗效果,但越来越多的证据表明,遗传和生理差异可能与这些疾病差异有关。

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