Chen Yuan, Wang Junlin, Xu Peiwei, Xiang Jie, Xu Dandan, Cheng Ping, Wang Xiaofeng, Wu Lizhi, Zhang Nianhua, Chen Zhijian
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Front Public Health. 2022 Aug 11;10:963257. doi: 10.3389/fpubh.2022.963257. eCollection 2022.
Antidepressants have aroused wide public concern due to their widespread presence in water and their harm to human health and environment. This study was designed to evaluate the contribution of wastewater treatment plants (WWTPs) to the presence of antidepressants in the surface water.
Data was evaluated by analyzing water samples collected from the influent, effluent, upstream and downstream of the WWTPs on the rivers of interest in Hangzhou, Zhejiang Province, China. Besides, the study also assessed the impact of the release of antidepressants from WWTPs to the surface water on the drinking water. An automatic solid-phase extraction combined with ultra-high performance liquid chromatography-tandem triple quadrupole mass spectrometry (UPLC-MS/MS) was used to detect antidepressants.
The most abundant compound was venlafaxine, followed by citalopram, sertraline, and fluvoxamine with concentrations between 0.6 and 87 ng/L. Antidepressants showed maximum concentrations at the effluent outlets of the WWTPs, and greater concentrations were found downstream than upstream of the WWTPs in Qiantang River. The results of source water and finished water showed that the detection concentration was lower than the detection limit of the method.
The less impact of the release of antidepressants from WWTPs to the surface water on the drinking water was identified. Nevertheless, these compounds were hardly removed by wastewater treatment processes. Thus, their risks deserve close attention.
抗抑郁药因其在水体中广泛存在及其对人类健康和环境的危害而引起了公众的广泛关注。本研究旨在评估污水处理厂（WWTPs）对地表水中抗抑郁药存在情况的贡献。
通过分析从中国浙江省杭州市相关河流上污水处理厂的进水、出水、上游和下游采集的水样来评估数据。此外，该研究还评估了污水处理厂向地表水排放抗抑郁药对饮用水的影响。采用自动固相萃取结合超高效液相色谱 - 串联三重四极杆质谱（UPLC-MS/MS）来检测抗抑郁药。
含量最高的化合物是文拉法辛，其次是西酞普兰、舍曲林和氟伏沙明，浓度在0.6至87纳克/升之间。抗抑郁药在污水处理厂的出水排放口处浓度最高，在钱塘江中，污水处理厂下游的浓度高于上游。原水和成品水的结果表明，检测浓度低于该方法的检测限。
已确定污水处理厂向地表水排放抗抑郁药对饮用水的影响较小。然而，这些化合物很难通过污水处理工艺去除。因此，它们的风险值得密切关注。
