非结核分枝杆菌肺病：趋势、危险因素、诊断与管理综述
Non-tuberculous mycobacteria pulmonary disease: A review of trends, risk factors, diagnosis and management.
作者信息
Nqwata L, Ouédrago A R
机构信息
Division of Pulmonology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Division of Pulmonology, Training and Research Unit in Health Sciences, University Joseph KI-ZEBRO, Ouagadougou, Burkina Faso.
出版信息
Afr J Thorac Crit Care Med. 2022 Jul 15;28(2). doi: 10.7196/AJTCCM.2022.v28i2.157. eCollection 2022.
Abstract
Non-tuberculous mycobacteria (NTM) reports have been on the rise globally, with increasing incidence and prevalence accompanied by poor outcomes. The rise has been attributed to an ageing population with increasing comorbid illnesses, and improved laboratory techniques in diagnosing the disease. However, despite the increase, some parts of the world still lack data, especially sub-Saharan African countries. The lack of data in our setting is difficult to explain, as we have a significant burden of NTM risk factors (i.e. HIV, tuberculosis and bronchiectasis). This review therefore serves as a reminder and a challenge to start searching, and reporting on our experiences. The review will highlight the rising incidence, important risk factors, diagnosis and management of NTM pulmonary disease.
摘要
非结核分枝杆菌（NTM）的报告在全球范围内呈上升趋势，发病率和患病率不断增加，同时预后不佳。这种上升归因于人口老龄化、合并症增多以及疾病诊断实验室技术的改进。然而，尽管有所增加，但世界上一些地区仍然缺乏数据，特别是撒哈拉以南非洲国家。我们所在地区缺乏数据难以解释，因为我们有大量的NTM风险因素（即艾滋病毒、结核病和支气管扩张）。因此，本综述旨在提醒并促使大家开始探索并报告我们的经验。该综述将重点介绍NTM肺病发病率的上升、重要风险因素、诊断和管理。
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