• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

近端受累型平山病的影像学和电生理特征：一项回顾性研究。

The radiological and electrophysiological characteristics of Hirayama disease with proximal involvement: A retrospective study.

作者信息

Wang Hongwei, Tian Ye, Wu Jianwei, Sun Chi, Nie Cong, Zheng Chaojun, Zou Fei, Xia Xinlei, Ma Xiaosheng, Lyu Feizhou, Jiang Jianyuan, Wang Hongli

机构信息

Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China.

Spine Center Fudan University, Shanghai, China.

出版信息

Front Neurol. 2022 Aug 11;13:969484. doi: 10.3389/fneur.2022.969484. eCollection 2022.

DOI:10.3389/fneur.2022.969484
PMID:36034284
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9406812/
Abstract

PURPOSE

Hirayama disease (HD) has been largely believed to affect only distal muscles. However, the proximal upper extremities have been affected in some cases, which can be confused with motor neuron diseases.

METHODS

Baseline data, deep tendon reflex, Hoffmann sign, cervical curvature, sagittal Cobb angle, atrophied spinal cord, high signal intensity, loss of attachment, and affected muscles and segments on electromyography (EMG) were retrospectively obtained and compared between patients with HD with proximal involvement and patients with simple distal HD in one center from September 2007 to April 2022.

RESULTS

In this study, fifteen patients with proximal HD and 30 patients with simple distal HD were included. The proximal group had a larger proportion of patients with decreased biceps reflex, decreased triceps reflex, brisk or hyperactive knee reflex, positive Hoffmann sign, and cervical kyphosis. The curvatures of the upper part of the cervical spine (C2-4) were lost to a greater degree in the proximal group. More affected segments were observed on magnetic resonance imaging (MRI) and electromyography in the proximal group.

CONCLUSION

The injured segments were longer and the upper curvature of the cervical spine was poorer in patients with HD with proximal involvement. These findings indicated that proximal involvement may indicate more serious HD.

摘要

目的

平山病（HD）一直被广泛认为仅累及远端肌肉。然而，在某些病例中，近端上肢也会受到影响，这可能会与运动神经元病相混淆。

方法

回顾性获取2007年9月至2022年4月期间在一个中心就诊的近端受累的HD患者和单纯远端HD患者的基线数据、深腱反射、霍夫曼征、颈椎曲度、矢状面Cobb角、脊髓萎缩、高信号强度、附着丧失以及肌电图（EMG）检查中受累的肌肉和节段，并进行比较。

结果

本研究纳入了15例近端HD患者和30例单纯远端HD患者。近端组中肱二头肌反射减弱、肱三头肌反射减弱、膝反射亢进或活跃、霍夫曼征阳性以及颈椎后凸的患者比例更高。近端组颈椎上部（C2 - 4）的曲度丧失程度更大。在近端组的磁共振成像（MRI）和肌电图检查中观察到更多受累节段。

结论

近端受累的HD患者损伤节段更长，颈椎上曲度更差。这些发现表明近端受累可能提示HD病情更严重。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/3297409fd4a1/fneur-13-969484-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/9f6f01678607/fneur-13-969484-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/13f1355bc3ec/fneur-13-969484-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/a3464b25b66a/fneur-13-969484-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/527b770e4ae4/fneur-13-969484-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/3297409fd4a1/fneur-13-969484-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/9f6f01678607/fneur-13-969484-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/13f1355bc3ec/fneur-13-969484-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/a3464b25b66a/fneur-13-969484-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/527b770e4ae4/fneur-13-969484-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a5/9406812/3297409fd4a1/fneur-13-969484-g0005.jpg

相似文献

1
The radiological and electrophysiological characteristics of Hirayama disease with proximal involvement: A retrospective study.近端受累型平山病的影像学和电生理特征：一项回顾性研究。
Front Neurol. 2022 Aug 11;13:969484. doi: 10.3389/fneur.2022.969484. eCollection 2022.
2
Hirayama's disease: an Italian single center experience and review of the literature.平山病：意大利单中心经验及文献综述
Quant Imaging Med Surg. 2016 Aug;6(4):364-373. doi: 10.21037/qims.2016.07.08.
3
Why the patients with Hirayama disease have abnormal cervical sagittal alignment? A radiological measurement analysis of posterior cervical extensors.平山病患者的颈椎矢状位排列为何异常？颈椎伸肌的影像学测量分析。
J Orthop Surg Res. 2022 Jan 15;17(1):19. doi: 10.1186/s13018-021-02905-5.
4
Quantitative assessment of motor impairment and surgical outcome in Hirayama disease with proximal involvement using motor unit number index.应用运动单位数量指数定量评估近端受累型平山病的运动障碍和手术效果。
Neurophysiol Clin. 2021 Aug;51(4):375-386. doi: 10.1016/j.neucli.2021.02.002. Epub 2021 Mar 3.
5
[A case of proximal-type Hirayama disease associated with neck axial rotation].1例与颈部轴向旋转相关的近端型平山病
Rinsho Shinkeigaku. 2021 Feb 23;61(2):120-126. doi: 10.5692/clinicalneurol.cn-001513. Epub 2021 Jan 26.
6
Update on the Pathogenesis, Clinical Diagnosis, and Treatment of Hirayama Disease.平山病的发病机制、临床诊断及治疗进展
Front Neurol. 2022 Feb 1;12:811943. doi: 10.3389/fneur.2021.811943. eCollection 2021.
7
Role of Dynamic Magnetic Resonance Imaging in Hirayama Disease, a Rare Motor Neuron Disease.动态磁共振成像在平山病（一种罕见的运动神经元疾病）中的作用
Cureus. 2022 Nov 4;14(11):e31099. doi: 10.7759/cureus.31099. eCollection 2022 Nov.
8
Hirayama disease: analysis of cases in Russia.平山病：俄罗斯病例分析。
Neurol Sci. 2019 Jan;40(1):105-112. doi: 10.1007/s10072-018-3588-7. Epub 2018 Oct 3.
9
Loss of cervical sagittal alignment worsens the cervical spinal lesions in patients with Hirayama disease.平山病患者颈椎矢状面排列失序会加重颈椎脊髓病变。
Neurol Sci. 2023 Jun;44(6):2103-2111. doi: 10.1007/s10072-023-06621-2. Epub 2023 Jan 26.
10
Clinical profile and dynamic magnetic resonance imaging in Hirayama disease: a single-centered cross-sectional study in Nepal.平山病的临床特征与动态磁共振成像：尼泊尔一项单中心横断面研究
Ann Med Surg (Lond). 2023 Apr 14;85(5):1750-1754. doi: 10.1097/MS9.0000000000000664. eCollection 2023 May.

引用本文的文献

1
Radiological and Electrophysiological Correlates of Disease Progression in Patients with Hirayama Disease.平山病患者疾病进展的影像学和电生理相关性
Ann Indian Acad Neurol. 2025 Jul 1;28(4):527-534. doi: 10.4103/aian.aian_8_25. Epub 2025 Aug 7.
2
In-Depth Understanding of Hirayama Disease: Dural Detachment Beyond Cervical Spine.平山病的深入理解：硬脊膜脱离超越颈椎范围
Ann Indian Acad Neurol. 2025 Jul 1;28(4):574-578. doi: 10.4103/aian.aian_16_25. Epub 2025 Apr 22.
3
Characteristics of Hirayama Disease in Young South Korean Soldiers.

本文引用的文献

1
Update on the Pathogenesis, Clinical Diagnosis, and Treatment of Hirayama Disease.平山病的发病机制、临床诊断及治疗进展
Front Neurol. 2022 Feb 1;12:811943. doi: 10.3389/fneur.2021.811943. eCollection 2021.
2
Why the patients with Hirayama disease have abnormal cervical sagittal alignment? A radiological measurement analysis of posterior cervical extensors.平山病患者的颈椎矢状位排列为何异常？颈椎伸肌的影像学测量分析。
J Orthop Surg Res. 2022 Jan 15;17(1):19. doi: 10.1186/s13018-021-02905-5.
3
Magnetic resonance imaging features of "Proximal" hirayama disease: Case report and literature review.
韩国年轻士兵平山病的特征
J Clin Neurol. 2024 May;20(3):293-299. doi: 10.3988/jcn.2023.0244. Epub 2024 Feb 5.
“近端型”平山病的磁共振成像特征：病例报告及文献复习
Surg Neurol Int. 2021 Dec 20;12:622. doi: 10.25259/SNI_1081_2021. eCollection 2021.
4
Interobserver and Intraobserver Reproducibility and Reliability of the Huashan Clinical Classification System for Hirayama Disease.华山平山病临床分类系统的观察者间及观察者内可重复性和可靠性
Front Neurol. 2021 Dec 3;12:779438. doi: 10.3389/fneur.2021.779438. eCollection 2021.
5
Quantitative assessment of motor impairment and surgical outcome in Hirayama disease with proximal involvement using motor unit number index.应用运动单位数量指数定量评估近端受累型平山病的运动障碍和手术效果。
Neurophysiol Clin. 2021 Aug;51(4):375-386. doi: 10.1016/j.neucli.2021.02.002. Epub 2021 Mar 3.
6
Establishment of a clinician-led guideline on the diagnosis and treatment of Hirayama disease using a modified Delphi technique.采用改良 Delphi 技术制定以临床医生为主导的平山病诊断与治疗指南。
Clin Neurophysiol. 2020 Jun;131(6):1311-1319. doi: 10.1016/j.clinph.2020.02.022. Epub 2020 Mar 16.
7
A 34-Year-Old Female Patient with Hirayama Disease Complicated by Severe Spinal Cord Injury.一位 34 岁女性平山病患者合并严重脊髓损伤。
World Neurosurg. 2019 Oct;130:84-88. doi: 10.1016/j.wneu.2019.06.208. Epub 2019 Jul 5.
8
Juvenile Muscular Atrophy of the Proximal Upper Extremity as So-Called Proximal-Type Hirayama Disease: Case Report and Review of the Literature.青少年近端上肢肌肉萎缩即所谓的近端型平山病：病例报告及文献综述
Case Rep Neurol. 2019 Mar 21;11(1):106-111. doi: 10.1159/000495606. eCollection 2019 Jan-Apr.
9
Severe cervical flexion myelopathy with long tract signs: a case report and a review of literature.伴有长束征的严重颈椎屈曲型脊髓病：一例报告并文献复习
Spinal Cord Ser Cases. 2017 May 11;3:17016. doi: 10.1038/scsandc.2017.16. eCollection 2017.
10
Clinical Experiences of Uncommon Motor Neuron Disease: Hirayama Disease.罕见运动神经元病——平山病的临床经验
Korean J Spine. 2016 Sep;13(3):170-172. doi: 10.14245/kjs.2016.13.3.170. Epub 2016 Sep 30.