奥地利的HLA - D分型。一项使用26个新定义的纯合分型细胞的分组研究。

HLA-D typing in Austria. A panel study using 26 newly defined homozygous typing cells.

作者信息

Hajek-Rosenmayr A, Obergruber G, Mayr W R

出版信息

Tissue Antigens. 1987 Feb;29(2):93-100. doi: 10.1111/j.1399-0039.1987.tb01557.x.

DOI:10.1111/j.1399-0039.1987.tb01557.x

Abstract

A panel of 120 HLA-A, -B, -C and -DR typed Austrians has been typed for HLA-D by the use of 26 Homozygous Typing Cells (HTC). The new Austrian HTC, partly defined by the 9th International Histocompatibility Workshop (9WS), partly by a checkerboard experiment with internationally well defined reference HTC, type for HLA-Dw1 to -Dw7 and an obviously new, so far unknown HLA-DR2 related HLA-D determinant. Associations of HLA-DR and HLA-D antigens in Austria and their frequencies are determined. Antigen frequencies in Austria are compared to frequencies in other Caucasoid populations.

摘要

利用26个纯合分型细胞（HTC）对一组120名已进行HLA - A、- B、- C和 - DR分型的奥地利人进行了HLA - D分型。新的奥地利HTC，部分由第9届国际组织相容性研讨会（9WS）定义，部分通过与国际上定义明确的参考HTC进行棋盘试验得出，可对HLA - Dw1至 - Dw7以及一个明显新的、迄今未知的与HLA - DR2相关的HLA - D决定簇进行分型。确定了奥地利HLA - DR和HLA - D抗原的关联及其频率。将奥地利的抗原频率与其他高加索人群的频率进行了比较。