Pradhan Aishwarya Umesh, Uwishema Olivier, Wellington Jack, Nisingizwe Philemon, Thambi Vimala Devi, Onyeaka Chinyere Vivian Patrick, Onyeaka Helen
Oli Health Magazine Organization, Research and Education, Kigali, Rwanda.
Clinton Global Initiative University, New York, USA.
Ann Med Surg (Lond). 2022 Sep;81:104414. doi: 10.1016/j.amsu.2022.104414. Epub 2022 Aug 20.
Chagas Disease (CD) is an infectious, neglected tropical disease (NTD) that has affected over 1.7 billion people worldwide. Unfortunately, most countries usually put little effort into mitigating the spread of NTDs, having weak public health approaches, diagnostic delays, and ineffective clinical management guidelines and resources. However, the ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by the coronavirus SARS-CoV-2, exacerbates the impact of NTDs. In this review, we examine the subsequent changes that have been imposed on CD prevention and treatment. Articles from Google Scholar and PubMed were extracted which satisfied our inclusion criteria. From our data, we gather that COVID-19 has - from preventive measures to treating patients - greatly affected every stage in the fight against CD. For instance, co-infection of CD and COVID-19 puts patients at higher risk for cardiomyopathy (i.e., atrial fibrillation, chronic heart failure), yet no clinical guidelines were established for co-infected patients. To mitigate the spread of CD during the COVID-19 pandemic, further investigations on the impacts of co-infections and vaccines that can be developed to treat such conditions are warranted.
恰加斯病（CD）是一种传染性的被忽视热带病（NTD），全球超过17亿人受到其影响。不幸的是，大多数国家通常在减轻NTD传播方面投入甚少，公共卫生措施薄弱，诊断延误，临床管理指南和资源无效。然而，由冠状病毒SARS-CoV-2引起的2019年冠状病毒病（COVID-19）大流行加剧了NTD的影响。在本综述中，我们研究了对CD预防和治疗产生的后续变化。从谷歌学术和PubMed中提取了符合我们纳入标准的文章。从我们的数据中，我们了解到COVID-19从预防措施到治疗患者，在抗击CD的各个阶段都产生了巨大影响。例如，CD和COVID-19的合并感染使患者患心肌病（即心房颤动、慢性心力衰竭）的风险更高，但尚未为合并感染患者制定临床指南。为了在COVID-19大流行期间减轻CD的传播，有必要进一步研究合并感染的影响以及可开发用于治疗此类病症的疫苗。
