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[工业频率交变磁场对大鼠肝脏脂质成分的影响]

[Effect of an alternating magnetic field of industrial frequency on the lipid composition of the rat liver].

作者信息

Chernysheva O N

出版信息

Ukr Biokhim Zh (1978). 1987 May-Jun;59(3):91-4.

PMID:3603741
Abstract

Multiple application (15 runs for 5 hours a day) of an alternative magnetic field of industrial frequency causes changes in lipid spectrum and phospholipid fractional composition of mitochondria and postmitochondrial fraction in rat liver. A decrease in the level of free fatty acids, triglycerides and cholesterol esters in mitochondria is registered, which presumably indicates an increase of the fats use in the cell's energetics. Changes in the phospholipid composition of mitochondria are negligible. In contrast to mitochondria, accumulation of lipids--triglycerides, cholesterol and its esters against a background of disbalance in phospholipid composition is established, which may presumably be one of the reasons for development of destructive infringements in the liver parenchyma during application of the alternating magnetic field.

摘要

每天5小时进行15次工业频率交变磁场的多次施加,会导致大鼠肝脏线粒体及线粒体后组分的脂质谱和磷脂组分发生变化。线粒体中游离脂肪酸、甘油三酯和胆固醇酯水平降低,这可能表明细胞能量代谢中脂肪利用增加。线粒体磷脂组成的变化可忽略不计。与线粒体相反,在磷脂组成失衡的背景下,脂质——甘油三酯、胆固醇及其酯类会积累,这可能是交变磁场作用期间肝脏实质发生破坏性损伤的原因之一。

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