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钛-聚醚醚酮牙科植入物在骨中的生物力学性能:计算机模拟分析

Biomechanical performance of Ti-PEEK dental implants in bone: An in-silico analysis.

作者信息

Ouldyerou Abdelhak, Merdji Ali, Aminallah Laid, Roy Sandipan, Mehboob Hassan, Özcan Mutlu

机构信息

Department of Mechanical Engineering, Faculty of Science and Technology, University of Mascara, Algeria.

Department of Mechanical Engineering, Faculty of Science and Technology, University of Mascara, Algeria; Laboratory of Mechanics Physics of Materials (LMPM), Faculty of Technology, Djillali Liabes University, Sidi Bel-Abbes, 22000, Algeria.

出版信息

J Mech Behav Biomed Mater. 2022 Oct;134:105422. doi: 10.1016/j.jmbbm.2022.105422. Epub 2022 Aug 22.

Abstract

Stress-shielding is caused by a significant mismatch in stiffness between bone tissue and Ti alloy dental implants. Therefore, in this study, a Ti-PEEK composite implant was examined and compared with conventional titanium, to determine the behavior of the host bone. Twelve 3D finite element models were modeled with two conditions of marginal cortical bone (with and without marginal bone loss). Six implant designs were constructed. Implant (A) was made with a conventional design (dense titanium), implants (B), (C) and (D) are designed with Ti-PEEK composite (outer layer made of PEEK and inner structures made of Ti with hexagonal, cylindrical, and cross shapes for implants (B), (C) and (D), respectively), the implant (E) is designed with Ti at the upper half section and PEEK at the bottom half section, and the implant (F) is designed with PEEK at the upper half section and Ti at the bottom half section. An axial load of 200 N was applied to the buccal cusp and central fossa of the occlusal surface. The displacements, stress, and equivalent strain were analyzed at the level of bone tissue. The mechanostat of Frost was used to determine the behavior of the cancellous bone under these biomechanical conditions. Results showed that strains were greater in cancellous bone with marginal bone loss than in healthy bone (w/o MBL). When compared to implants (B)-(F), conventional implant (A) did not produce as much strain. Thus, results and analyses suggest that the Ti-PEEK implants outperform compared with the implant (A) in the case of no marginal bone loss. However, the implants (A) and (E) perform equally in terms of bone loss.

摘要

应力屏蔽是由骨组织与钛合金牙科植入物之间显著的刚度不匹配引起的。因此,在本研究中,对一种钛-聚醚醚酮(Ti-PEEK)复合植入物进行了研究,并与传统钛植入物进行比较,以确定宿主骨的行为。构建了12个三维有限元模型,模拟两种边缘皮质骨情况(有和没有边缘骨丢失)。设计了六种植入物。植入物(A)采用传统设计(致密钛),植入物(B)、(C)和(D)采用Ti-PEEK复合材料设计(外层由PEEK制成,内部结构由Ti制成,植入物(B)、(C)和(D)的内部结构分别为六边形、圆柱形和十字形),植入物(E)上半部分采用Ti设计,下半部分采用PEEK设计,植入物(F)上半部分采用PEEK设计,下半部分采用Ti设计。在咬合面的颊尖和中央窝施加200 N的轴向载荷。在骨组织水平分析位移、应力和等效应变。采用Frost的机械稳态理论来确定松质骨在这些生物力学条件下的行为。结果表明,有边缘骨丢失的松质骨中的应变大于健康骨(无边缘骨丢失)中的应变。与植入物(B)-(F)相比,传统植入物(A)产生的应变没有那么大。因此,结果和分析表明,在没有边缘骨丢失的情况下,Ti-PEEK植入物的性能优于植入物(A)。然而,在骨丢失方面,植入物(A)和(E)的表现相当。

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