Infectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy.
University of Milan, Milan, Italy.
Antimicrob Resist Infect Control. 2022 Aug 29;11(1):108. doi: 10.1186/s13756-022-01152-5.
Discontinuation of antimicrobial stewardship programs (ASPs) and increased antibiotic use were described during SARS-CoV-2 pandemic. In order to measure COVID-19 impact on ASPs in a setting of high multidrug resistance organisms (MDRO) prevalence, a qualitative survey was designed. In July 2021, eighteen ID Units were asked to answer a questionnaire about their hospital characteristics, ASPs implementation status before the pandemic and impact of SARS-CoV-2 pandemic on ASPs after the 1st and 2nd pandemic waves in Italy. Nine ID centres (50%) reported a reduction of ASPs and in 7 cases (38.9%) these were suspended. After the early pandemic waves, the proportion of centres that restarted their ASPs was higher among the ID centres where antimicrobial stewardship was formally identified as a priority objective (9/11, 82%, vs 2/7, 28%). SARS-CoV-2 pandemic had a severe impact in ASPs in a region highly affected by COVID-19 and antimicrobial resistance but weaknesses related to the pre-existent ASPs might have played a role.
在 SARS-CoV-2 大流行期间，有研究描述了抗菌药物管理项目 (ASPs) 的中断和抗生素使用的增加。为了在高多重耐药菌 (MDRO) 流行的环境下衡量 COVID-19 对 ASPs 的影响，设计了一项定性调查。2021 年 7 月，18 个 ID 单位被要求回答一份关于其医院特征、大流行前 ASPs 实施情况以及 SARS-CoV-2 大流行对意大利第一波和第二波后 ASPs 影响的问卷。9 个 ID 中心（50%）报告 ASPs 减少，其中 7 例（38.9%）暂停。在早期大流行浪潮之后，在将抗菌药物管理正式确定为优先目标的 ID 中心中，重新启动其 ASPs 的中心比例更高（9/11，82%，vs. 2/7，28%）。COVID-19 和抗菌药物耐药性高度流行的地区的 ASPs 受到了严重影响，但与先前存在的 ASPs 相关的弱点可能也起到了一定作用。
