Ramos-Yataco Anthony, Salcedo Davila Emanuel A, Meza Kelly, Harbuz-Miller Inga
Internal Medicine, Hospital Ricardo Cruzado Rivarola, Nasca, PER.
Department of Medical Education, Ricardo Palma University, Lima, PER.
Cureus. 2022 Jul 26;14(7):e27272. doi: 10.7759/cureus.27272. eCollection 2022 Jul.
Type 2 diabetes mellitus (T2DM) has been recognized as a risk factor for severe coronavirus disease 2019 (COVID-19) infection, and COVID-19 in diabetic patients is associated with a poor prognosis. New evidence suggests that patients with T2DM may experience diabetic ketoacidosis (DKA) or hyperglycemic hyperosmolar state (HHS) if infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is limited literature on new-onset diabetes in patients infected by SARS-CoV-2 without a history of diabetes. We present a case series of three patients who developed new-onset diabetes while suffering from acute COVID-19 infection; they presented with DKA even though they had no prior history or risk factors for diabetes. They remain persistently insulin-dependent several months post-recovery.
2型糖尿病（T2DM）已被公认为是2019冠状病毒病（COVID-19）严重感染的一个风险因素，糖尿病患者感染COVID-19后预后较差。新证据表明，2型糖尿病患者如果感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2），可能会出现糖尿病酮症酸中毒（DKA）或高血糖高渗状态（HHS）。然而，关于无糖尿病病史的SARS-CoV-2感染患者新发糖尿病的文献有限。我们报告了一个病例系列，三名患者在患急性COVID-19感染时出现新发糖尿病；尽管他们既往无糖尿病病史或风险因素，但均表现为DKA。康复后数月，他们仍持续依赖胰岛素治疗。
