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严重急性呼吸综合征冠状病毒2(新冠病毒)与内分泌系统

SARS-CoV-2 (COVID-19) and the Endocrine System.

作者信息

Lundholm Michelle D, Poku Caroline, Emanuele Nicholas, Emanuele Mary Ann, Lopez Norma

机构信息

Department of Internal Medicine, Loyola University Medical Center, Maywood, Illinois.

Department of Medicine, Division of Endocrinology, Loyola University Health Care System, Maywood, Illinois.

出版信息

J Endocr Soc. 2020 Oct 1;4(11):bvaa144. doi: 10.1210/jendso/bvaa144. eCollection 2020 Nov 1.

Abstract

As SARS-CoV-2 (COVID-19) overtakes the world, causing moderate to severe disease in about 15% of infected patients, COVID-19 is also found to have widespread effects throughout the body with a myriad of clinical manifestations including the endocrine system. This manuscript reviews what is known about the impact of COVID-19 on the pathophysiology and management of diabetes (both outpatient and inpatient) as well as pituitary, adrenal, thyroid, bone, and gonadal function. Findings in this area are evolving, and long-term effects of infection remain an active area of further research.

摘要

随着严重急性呼吸综合征冠状病毒2(SARS-CoV-2,即新冠病毒)席卷全球,约15%的感染患者会出现中度至重度疾病,人们还发现新冠病毒会对全身产生广泛影响,出现包括内分泌系统在内的众多临床表现。本文综述了关于新冠病毒对糖尿病(门诊和住院患者)以及垂体、肾上腺、甲状腺、骨骼和性腺功能的病理生理学及管理的影响的已知情况。该领域的研究结果不断发展,感染的长期影响仍是一个有待进一步深入研究的活跃领域。

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