Division of Allergy, Immunology and Rheumatology, University of California San Diego School of Medicine, La Jolla, California.
University of Toledo, Toledo, Ohio.
Ann Allergy Asthma Immunol. 2022 Dec;129(6):731-736. doi: 10.1016/j.anai.2022.08.993. Epub 2022 Aug 27.
Chronic cough (CC) affects 11% of the US adult population, and these patients experience persistent symptoms despite adherence to recommended treatment protocols. Further research is needed to identify effective therapies to treat CC.
To describe the referral sources, etiology, prevalence, symptoms, and treatments for patients diagnosed with having CC who present to allergy specialists (AS).
An online survey was administered to 177 AS. The survey queried each AS experience with patients with CC, including the prevalence of CC, source of referrals for patients with CC, and perceived efficacy of treatments.
A total of 103 (58%) AS reported that the patients with CC they treated were primarily of female sex (58.26%) and White (65.69%). Family physicians, nurse practitioners, physician assistants, and primary care internists were the most common source of referrals of patients with CC to AS. Furthermore, 20% of the respondents reported a complete resolution of the symptoms for more than 75% of their patients with CC. The top 4 "very common complaints" reported by the patients with CC were social embarrassment, loss of sleep, decreased quality of life, and sleep disruption. The top 4 most frequent treatments prescribed for CC were antireflux treatments, inhaled corticosteroids alone or in combination with long-acting β-agonist, short-acting bronchodilators, and first-generation antihistamines. None of the therapies were rated "very effective" in greater than 50% of the patients with CC.
The available treatments for CC do not effectively resolve the symptoms of this condition, and additional treatments need to be developed.
慢性咳嗽（CC）影响了美国 11%的成年人口，这些患者尽管遵循了推荐的治疗方案，但仍持续存在症状。需要进一步研究以确定有效的治疗方法来治疗 CC。
描述向过敏专家（AS）就诊的诊断为 CC 的患者的转诊来源、病因、患病率、症状和治疗方法。
对 177 名 AS 进行了在线调查。该调查询问了每位 AS 与 CC 患者的相关经历，包括 CC 的患病率、CC 患者的转诊来源以及治疗效果的看法。
共有 103 名（58%）AS 报告称，他们治疗的 CC 患者主要为女性（58.26%）和白人（65.69%）。家庭医生、护士从业者、医师助理和初级保健内科医生是将 CC 患者转诊给 AS 的最常见来源。此外，20%的受访者报告称，他们的 CC 患者中有超过 75%的症状完全缓解。CC 患者报告的前 4 个“常见抱怨”是社交尴尬、睡眠损失、生活质量下降和睡眠中断。CC 最常开的前 4 种治疗方法是抗反流治疗、单独吸入皮质类固醇或与长效β-激动剂联合使用、短效支气管扩张剂和第一代抗组胺药。没有一种治疗方法在超过 50%的 CC 患者中被评为“非常有效”。
目前 CC 的治疗方法无法有效缓解该病症的症状，需要开发新的治疗方法。
