Tonozuka Ryosuke, Itoi Takao, Nagai Kazumasa, Sofuni Atsushi, Tsuchiya Takayoshi, Ishii Kentaro, Tanaka Reina, Mukai Shuntaro, Minami Hirohito, Yamamoto Kenjiro
Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
J Hepatobiliary Pancreat Sci. 2023 Mar;30(3):401-407. doi: 10.1002/jhbp.1231. Epub 2022 Sep 15.
BACKGROUND/PURPOSE: A peroral cholangioscope (POCS) can allow direct visualization of the biliary mucosa and its use is becoming more widespread due to improvements in functionality, image quality, and operability, as well as the development of related devices. Recently, a novel mother-baby peroral cholangioscope (nMB-POCS) with a large (2-mm) accessory channel has been developed. In this study, we evaluated the feasibility of this novel POCS in a dry simulation and animal model.
We evaluated the ease of insertion and maneuverability of the nMB-POCS, the image quality, and the passage of the devices into the accessory channel and into the common bile duct in a dry and live porcine model.
In both models, the nMB-POCS could be easily inserted into the duodenoscope and into the distal bile duct and hilum. The image quality was good, and it was possible to observe the surface structure and the vascular network of the bile duct mucosa in detail.
The nMB-POCS with its larger accessory channel is expected to improve the efficiency of diagnosis and treatment, and reduce the procedure time. Clinical studies in patients are warranted.
背景/目的：经口胆道镜（POCS）可直接观察胆道黏膜，随着其功能、图像质量和可操作性的改善以及相关设备的发展，其应用越来越广泛。最近，一种具有大（2毫米）附件通道的新型子母式经口胆道镜（nMB-POCS）已被开发出来。在本研究中，我们在干式模拟和动物模型中评估了这种新型POCS的可行性。
我们在干式和活体猪模型中评估了nMB-POCS的插入难易程度和可操作性、图像质量以及设备通过附件通道进入胆总管的情况。
在两个模型中，nMB-POCS都可以很容易地插入十二指肠镜并进入远端胆管和肝门。图像质量良好，能够详细观察胆管黏膜的表面结构和血管网络。
具有较大附件通道的nMB-POCS有望提高诊断和治疗效率，并缩短手术时间。有必要对患者进行临床研究。
