School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou, 221116, P. R. China.
School of Environmental and Safety Engineering, Changzhou University, Changzhou, 213164, Jiangsu, P. R. China.
Chem Commun (Camb). 2022 Sep 15;58(74):10420-10423. doi: 10.1039/d2cc03922b.
A new electrochemical selective annulative amino-ketalization and amino-oxygenation of 1,6-enynes with disulfonimides and alcohols is reported, producing a series of functionalized benzofurans under catalyst- and oxidant-free conditions. The annulative aminoketalization proceeds with simple short-chain alcohols such as methanol, ethanol and -propanol as -nucleophilic reagents, while the reaction occurs in the annulative aminooxygenation direction in the presence of water and large steric -butyl alcohol (SBA).
报告了一种新的电化学选择性环化氨基缩酮化和氨基氧化 1,6-烯炔与二磺酰亚胺和醇的反应，在无催化剂和氧化剂的条件下，生成了一系列功能化的苯并呋喃。环化氨基缩酮化反应可以使用甲醇、乙醇和异丙醇等简单的短链醇作为亲核试剂，而在水和大位阻叔丁醇（SBA）存在下，反应则以环化氨基氧化的方向进行。
