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使用光学相干断层扫描评估睑板腺功能障碍的泪膜。

Evaluation of the Tear Meniscus Using Optical Coherence Tomography in Meibomian Gland Dysfunction.

机构信息

Department of Ophthalmology, Tatvan State Hospital, Bitlis, Turkey.

出版信息

Ocul Immunol Inflamm. 2023 Nov;31(9):1785-1791. doi: 10.1080/09273948.2022.2113802. Epub 2022 Aug 31.

Abstract

INTRODUCTION

This study aimed to evaluate tear meniscus parameters in meibomian gland dysfunction (MGD) using optical coherence tomography and ImageJ software.

METHODS

We enrolled 66 eyes of 66 participants and measured tear meniscus parameters, including height, depth, turbidity, and percentage area occupied by particles (PAOP) in the meniscus in the MGD and control groups.

RESULTS

Tear meniscus turbidity and PAOP were significantly higher in the MGD group, but tear meniscus height (TMH) and depth (TMD) did not differ significantly between groups. Tear meniscus turbidity and PAOP were positively correlated with each other and ocular surface parameters, including OSDI and ocular surface staining scores.

CONCLUSION

Tear meniscus turbidity and PAOP were higher in the MGD group than in the control group; therefore, they can be used as significant non-invasive parameters in the prediction of MGD. TMH and TMD did not differ significantly between groups.

摘要

简介

本研究旨在使用光学相干断层扫描和 ImageJ 软件评估睑板腺功能障碍(MGD)患者的泪膜半月板参数。

方法

我们招募了 66 名参与者的 66 只眼睛,并测量了 MGD 组和对照组的泪膜半月板参数,包括高度、深度、混浊度和半月板内颗粒所占面积百分比(PAOP)。

结果

MGD 组的泪膜半月板混浊度和 PAOP 显著升高,但两组间的泪膜半月板高度(TMH)和深度(TMD)无显著差异。泪膜半月板混浊度和 PAOP 呈正相关,与眼表参数,包括 OSDI 和眼表染色评分也呈正相关。

结论

MGD 组的泪膜半月板混浊度和 PAOP 高于对照组;因此,它们可以作为预测 MGD 的重要非侵入性参数。两组间 TMH 和 TMD 无显著差异。

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