The State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science, Fudan University, Shanghai 200433, People's Republic of China.
Multiscale Research Institute for Complex Systems, Fudan University, Shanghai 200433, People's Republic of China.
J Am Chem Soc. 2022 Sep 14;144(36):16232-16251. doi: 10.1021/jacs.2c04418. Epub 2022 Aug 31.
The complexity and diversity of biomacromolecules make them a unique class of building blocks for generating precise assemblies. They are particularly available to a new generation of biomaterials integrated with living systems due to their intrinsic properties such as accurate recognition, self-organization, and adaptability. Therefore, many excellent approaches have been developed, leading to a variety of quite practical outcomes. Here, we review recent advances in the fabrication and application of artificially precise assemblies by employing proteins and carbohydrates as building blocks, followed by our perspectives on some of new challenges, goals, and opportunities for the future research directions in this field.
生物大分子的复杂性和多样性使它们成为生成精确组装体的独特一类构建块。由于其内在特性，如准确识别、自组织和适应性，它们特别适用于与生命系统集成的新一代生物材料。因此，已经开发出许多优秀的方法，导致了各种非常实用的结果。在这里，我们回顾了利用蛋白质和碳水化合物作为构建块来制造和应用人工精确组装体的最新进展，然后我们对该领域未来研究方向的一些新挑战、目标和机遇提出了看法。
