Hu Lina, Zhou Shujing, Zhang Xiumei, Shi Chengyang, Zhang Yifan, Chen Xiaoyi
School of Pharmacy, Jiamusi University, Jiamusi 154007, China.
Polymers (Basel). 2024 Jul 23;16(15):2097. doi: 10.3390/polym16152097.
Polymer self-assembly can prepare various shapes and sizes of pores, making it widely used. The complexity and diversity of biomolecules make them a unique class of building blocks for precise assembly. They are particularly suitable for the new generation of biomaterials integrated with life systems as they possess inherent characteristics such as accurate identification, self-organization, and adaptability. Therefore, many excellent methods developed have led to various practical results. At the same time, the development of advanced science and technology has also expanded the application scope of self-assembly of synthetic polymers. By utilizing this technology, materials with unique shapes and properties can be prepared and applied in the field of tissue engineering. Nanomaterials with transparent and conductive properties can be prepared and applied in fields such as electronic displays and smart glass. Multi-dimensional, controllable, and multi-level self-assembly between nanostructures has been achieved through quantitative control of polymer dosage and combination, chemical modification, and composite methods. Here, we list the classic applications of natural- and artificially synthesized polymer self-assembly in the fields of biomedicine and materials, introduce the cutting-edge technologies involved in these applications, and discuss in-depth the advantages, disadvantages, and future development directions of each type of polymer self-assembly.
聚合物自组装能够制备各种形状和尺寸的孔隙,因而得到广泛应用。生物分子的复杂性和多样性使其成为用于精确组装的独特一类构建单元。它们特别适合与生命系统集成的新一代生物材料,因为它们具有准确识别、自我组织和适应性等固有特性。因此,已开发出的许多优秀方法带来了各种实际成果。同时,先进科学技术的发展也拓展了合成聚合物自组装的应用范围。利用这项技术,可以制备具有独特形状和性能的材料,并应用于组织工程领域。可以制备具有透明和导电性能的纳米材料,并应用于电子显示和智能玻璃等领域。通过对聚合物用量和组合的定量控制、化学修饰以及复合方法,已实现了纳米结构之间的多维、可控和多级自组装。在此,我们列举天然和人工合成聚合物自组装在生物医学和材料领域的经典应用,介绍这些应用中涉及的前沿技术,并深入探讨每种类型聚合物自组装的优缺点及未来发展方向。