Characterization of an antimicrobial substance, produced by Streptomyces violaceorectus.

Streptomyces violaceorectus produces a yellow-brown antimicrobial substance when cultivated on starch-potassium nitrate medium. The purified antimicrobial substance was active against Gram-positive, Gram-negative bacteria, and fungi. The solubility, characteristics, Rf values, minimum inhibiting concentrations, UV and IR spectra were studied. Elemental analysis was: carbon 37.94%, hydrogen 6.97%, nitrogen 7.50%, and oxygen 47.58%.