针刺与抗高血压药物治疗原发性高血压的不良反应：贝叶斯网状 Meta 分析方案。

Adverse Reaction of Acupuncture and Antihypertensive Drugs for Treatment of Essential hypertension: A Protocol for Bayesian Network Meta-Analysis.

机构信息

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Acupuncture Department, Tianjin 300381, China.

Institution of Acupuncture and Moxibustion, China Academy of Traditional Medical Science, Beijing 100700, China.

出版信息

Comput Intell Neurosci. 2022 Aug 21;2022:7397307. doi: 10.1155/2022/7397307. eCollection 2022.

DOI:10.1155/2022/7397307

PMID:36045996

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9420606/

Abstract

BACKGROUND

Hypertension, as a high risk factor of cardiovascular disease, has led to a significant upward trend in the population and incidence of the disease. Hypertension patients need to take antihypertensive drugs for life, and therefore people gradually pay more attention to the adverse reactions of antihypertensive drugs. This study protocol outlines a plan to assess the adverse reaction of the different antihypertensive drugs and acupuncture in order for clinical application.

OBJECTIVE

To compare the side effects of different antihypertensive drugs and acupuncture in the treatment of hypertension.

METHODS

and analysis. We will search the databases containing CNKI, Wan-Fang database, Chinese Scientific Journal Database(VIP), PubMed, Cochrane, and Embase, and randomized controlled trials (RCTs) of commonly used antihypertensive drugs or acupuncture for primary hypertension will be obtained. Then, Stata14.0 and Gemtc will be used to assess the statistics. . Since no personal patient consent will be required in the study, there is no ethical approval. The results of this reporting will be submitted to a peer-reviewed publication. PROSPERO registration number: CRD42020152703.

摘要

背景

高血压作为心血管疾病的高危因素，导致其在人群中的发病率呈明显上升趋势。高血压患者需要终生服用降压药物，因此人们逐渐更加关注降压药物的不良反应。本研究方案旨在评估不同降压药物与针刺治疗高血压的不良反应，以便为临床应用提供参考。

目的

比较不同降压药物与针刺治疗高血压的不良反应。

方法

检索中国知网（CNKI）、万方数据库、维普中文科技期刊数据库（VIP）、PubMed、Cochrane、Embase 等数据库，纳入常用降压药物或针刺治疗原发性高血压的随机对照试验（RCT），采用 Stata14.0 及 Gemtc 进行统计学分析。由于本研究不需要征得患者的个人同意，因此无需伦理批准。本报告的结果将提交给同行评审的出版物。PROSPERO 注册号：CRD42020152703。