老年人的健康相关生活质量与降压药物治疗依从性。
Health-related quality of life and antihypertensive medication adherence among older adults.
机构信息
Center for Health Research, Ochsner Clinic Foundation, New Orleans, LA, USA.
出版信息
Age Ageing. 2010 Jul;39(4):481-7. doi: 10.1093/ageing/afq040. Epub 2010 May 31.
Abstract
PURPOSE
health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults.
METHODS
participants were part of a cohort study of older adults enrolled in a managed care organisation and treated for hypertension (n = 2,180). Physical and Mental Component Summary Scores (PCS and MCS) of HRQOL were assessed using the RAND Medical Outcomes Study 36-item tool. Adherence to antihypertensive medication was assessed with the eight-item Morisky Medication Adherence Scale.
RESULTS
the mean age of participants was 75.0 +/- 5.6 years, 69.3% were white, 58.5% were women and 14.1% had low antihypertensive medication adherence. Low HRQOL scores were associated with lower levels of antihypertensive medication adherence in older adults. After adjustment for covariates, those with low PCS and MCS scores were 1.33 (95% CI 1.01, 1.74) and 2.26 (95% CI 1.74, 2.97) times more likely, respectively, to have low antihypertensive medication adherence than those with PCS and MCS scores in the top 2 tertiles.
CONCLUSIONS
low HRQOL may be an important barrier to achieving high medication adherence.
摘要
目的
健康相关生活质量（HRQOL）是一个重要的心理社会特征，可能会影响个体管理慢性疾病的能力。我们研究了 HRQOL 与老年高血压患者降压药物治疗依从性之间的关系。
方法
参与者是一项在管理式医疗组织中招募的老年患者队列研究的一部分，患有高血压（n=2180）。使用 RAND 医疗结局研究 36 项工具评估 HRQOL 的身体和心理成分综合评分（PCS 和 MCS）。使用 Morisky 药物治疗依从性量表评估降压药物的依从性。
结果
参与者的平均年龄为 75.0±5.6 岁，69.3%为白人，58.5%为女性，14.1%的患者降压药物治疗依从性较低。HRQOL 评分较低与老年患者降压药物治疗依从性较低有关。在校正协变量后，PCS 和 MCS 评分较低的患者发生低降压药物治疗依从性的可能性分别为 PCS 和 MCS 评分较高的患者的 1.33（95%CI 1.01，1.74）和 2.26（95%CI 1.74，2.97）倍。
结论
HRQOL 较低可能是实现高药物治疗依从性的重要障碍。
相似文献
1
Health-related quality of life and antihypertensive medication adherence among older adults.老年人的健康相关生活质量与降压药物治疗依从性。
Age Ageing. 2010 Jul;39(4):481-7. doi: 10.1093/ageing/afq040. Epub 2010 May 31.
2
Examining the relationship between antihypertensive medication satisfaction and adherence in older patients.探讨老年患者降压药物满意度与依从性之间的关系。
Res Social Adm Pharm. 2017 May-Jun;13(3):602-613. doi: 10.1016/j.sapharm.2016.06.013. Epub 2016 Jul 9.
3
Low medication adherence is associated with decline in health-related quality of life: results of a longitudinal analysis among older women and men with hypertension.低药物依从性与健康相关生活质量下降有关：对高血压老年男女进行纵向分析的结果。
J Hypertens. 2021 Jan;39(1):153-161. doi: 10.1097/HJH.0000000000002590.
4
Quality of Life and Its Association With Treatment Satisfaction, Adherence to Medication, and Trust in Physician Among Patients With Hypertension: A Cross-Sectional Designed Study.高血压患者的生活质量及其与治疗满意度、药物依从性和对医生信任度的关联：一项横断面设计研究
J Cardiovasc Pharmacol Ther. 2018 Nov;23(6):532-542. doi: 10.1177/1074248418784292. Epub 2018 Jun 19.
5
Life events, coping, and antihypertensive medication adherence among older adults: the cohort study of medication adherence among older adults.老年人生活事件、应对方式与降压药物治疗依从性：老年人药物治疗依从性队列研究。
Am J Epidemiol. 2012 Oct 1;176 Suppl 7(Suppl 7):S64-71. doi: 10.1093/aje/kws233.
6
Association of depression with antihypertensive medication adherence in older adults: cross-sectional and longitudinal findings from CoSMO.老年人抑郁与抗高血压药物依从性的关系：CoSMO 的横断面和纵向研究结果。
Ann Behav Med. 2010 Dec;40(3):248-57. doi: 10.1007/s12160-010-9217-1.
7
Adverse effects of complementary and alternative medicine on antihypertensive medication adherence: findings from the cohort study of medication adherence among older adults.补充和替代医学对降压药物依从性的不良影响：老年人药物依从性队列研究的结果。
J Am Geriatr Soc. 2010 Jan;58(1):54-61. doi: 10.1111/j.1532-5415.2009.02639.x.
8
Sex differences in barriers to antihypertensive medication adherence: findings from the cohort study of medication adherence among older adults.老年患者药物治疗依从性队列研究中的发现：降压药物治疗依从性障碍的性别差异。
J Am Geriatr Soc. 2013 Apr;61(4):558-64. doi: 10.1111/jgs.12171. Epub 2013 Mar 25.
9
A hybrid 4-item Krousel-Wood Medication Adherence Scale predicts cardiovascular events in older hypertensive adults.一项混合的 4 项 Krousel-Wood 药物依从性量表可预测老年高血压患者的心血管事件。
J Hypertens. 2019 Apr;37(4):851-859. doi: 10.1097/HJH.0000000000001955.
10
Differences in cardiovascular disease risk when antihypertensive medication adherence is assessed by pharmacy fill versus self-report: the Cohort Study of Medication Adherence among Older Adults (CoSMO).通过药房配药记录与自我报告评估抗高血压药物依从性时心血管疾病风险的差异：老年人药物依从性队列研究（CoSMO）。
J Hypertens. 2015 Feb;33(2):412-20. doi: 10.1097/HJH.0000000000000382.
引用本文的文献
1
Pre-stroke Adherence to Hypertension Medications in a Bi-racial United States Stroke Belt.美国中风带中两种族人群中风前对高血压药物的依从性。
High Blood Press Cardiovasc Prev. 2023 Jul;30(4):333-336. doi: 10.1007/s40292-023-00581-6. Epub 2023 May 26.
2
Association between health-related quality of life and nonadherence to antihypertensive medication.健康相关生活质量与抗高血压药物治疗依从性的关系。
Nurs Open. 2023 Jun;10(6):3570-3578. doi: 10.1002/nop2.1599. Epub 2023 Jan 4.
3
A Critical Review of Medication Adherence in Hypertension: Barriers and Facilitators Clinicians Should Consider.高血压治疗中药物依从性的批判性综述：临床医生应考虑的障碍与促进因素
Patient Prefer Adherence. 2022 Oct 7;16:2749-2757. doi: 10.2147/PPA.S368784. eCollection 2022.
4
Adverse Reaction of Acupuncture and Antihypertensive Drugs for Treatment of Essential hypertension: A Protocol for Bayesian Network Meta-Analysis.针刺与抗高血压药物治疗原发性高血压的不良反应：贝叶斯网状 Meta 分析方案。
Comput Intell Neurosci. 2022 Aug 21;2022:7397307. doi: 10.1155/2022/7397307. eCollection 2022.
5
Evaluating the socio-demographic, economic and clinical (SDEC) factors on health related quality of life (HRQoL) of hypertensive patients using EQ-5D-5L scoring algorithm.评估 SDEC 因素对高血压患者健康相关生活质量（HRQoL）的影响，使用 EQ-5D-5L 评分算法。
PLoS One. 2022 Jun 30;17(6):e0270587. doi: 10.1371/journal.pone.0270587. eCollection 2022.
6
Strategies for improving the treatment and control of hypertension in Japan.日本改善高血压治疗与控制的策略。
J Hum Hypertens. 2024 Jun;38(6):510-515. doi: 10.1038/s41371-022-00708-7. Epub 2022 Jun 3.
7
Reasons behind high rate of non-compliance to scheduled office visits in hypertensive patients: results from the Egyptian registry of specialized hypertension clinics.高血压患者定期门诊就诊依从率高的背后原因：埃及高血压专科诊所登记结果
Egypt Heart J. 2022 May 31;74(1):45. doi: 10.1186/s43044-022-00285-7.
8
Patient Knowledge, Adherence to the Therapeutic Regimen, and Quality of Life in Hemodialysis : Knowledge, Adherence, and Quality of Life in Hemodialysis.血液透析患者的知识、治疗方案依从性和生活质量：血液透析中的知识、依从性和生活质量。
Adv Exp Med Biol. 2021;1337:259-272. doi: 10.1007/978-3-030-78771-4_29.
9
Medication Adherence and Blood Pressure Control: A Scientific Statement From the American Heart Association.药物依从性与血压控制：美国心脏协会的科学声明。
Hypertension. 2022 Jan;79(1):e1-e14. doi: 10.1161/HYP.0000000000000203. Epub 2021 Oct 7.
10
Adults' Adherence to Growth Hormone Replacement in Relation to Medication-Related Beliefs, Coping and Quality of Life - An Exploratory Analysis.成人对生长激素替代疗法的依从性与与药物相关的信念、应对方式和生活质量的关系——一项探索性分析。
Front Endocrinol (Lausanne). 2021 May 24;12:680964. doi: 10.3389/fendo.2021.680964. eCollection 2021.
本文引用的文献
1
Factors associated to patients' noncompliance with hypertension treatment.与患者高血压治疗依从性不佳相关的因素。
Rev Lat Am Enfermagem. 2009 Mar-Apr;17(2):201-6. doi: 10.1590/s0104-11692009000200010.
2
Associations between chronic disease, age and physical and mental health status.慢性病、年龄与身心健康状况之间的关联。
Chronic Dis Can. 2009;29(3):108-16.
3
Barriers to and determinants of medication adherence in hypertension management: perspective of the cohort study of medication adherence among older adults.高血压管理中药物依从性的障碍与决定因素：老年人药物依从性队列研究的视角
Med Clin North Am. 2009 May;93(3):753-69. doi: 10.1016/j.mcna.2009.02.007.
4
Reducing the health risks of diabetes: how self-determination theory may help improve medication adherence and quality of life.降低糖尿病的健康风险：自我决定理论如何有助于提高药物依从性和生活质量。
Diabetes Educ. 2009 May-Jun;35(3):484-92. doi: 10.1177/0145721709333856. Epub 2009 Mar 26.
5
Interrelationships of quality of life, compliance, clinical outcomes and life satisfaction: a cross-sectional study on hypertensive geriatrics.生活质量、依从性、临床结局与生活满意度之间的相互关系：一项老年高血压患者的横断面研究。
J Clin Pharm Ther. 1997 Oct-Dec;22(5-6):357-69. doi: 10.1111/j.1365-2710.1997.tb00019.x.
6
New medication adherence scale versus pharmacy fill rates in seniors with hypertension.老年高血压患者的新型药物依从性量表与药房配药率对比
Am J Manag Care. 2009 Jan;15(1):59-66.
7
The association of emotional well-being and marital status with treatment adherence among patients with hypertension.高血压患者的情绪健康和婚姻状况与治疗依从性之间的关联。
J Behav Med. 2008 Dec;31(6):489-97. doi: 10.1007/s10865-008-9173-4. Epub 2008 Sep 9.
8
Quality of life associated with treatment adherence in patients with type 2 diabetes: a cross-sectional study.2型糖尿病患者治疗依从性与生活质量的关系：一项横断面研究。
BMC Health Serv Res. 2008 Jul 30;8:164. doi: 10.1186/1472-6963-8-164.
9
Predictive validity of a medication adherence measure in an outpatient setting.门诊环境中药物依从性测量的预测效度。
J Clin Hypertens (Greenwich). 2008 May;10(5):348-54. doi: 10.1111/j.1751-7176.2008.07572.x.
10
Self-efficacy mediates the relationship between depressive symptoms and medication adherence among hypertensive African Americans.自我效能在非洲裔美国高血压患者的抑郁症状与药物依从性之间起中介作用。
Health Educ Behav. 2009 Feb;36(1):127-37. doi: 10.1177/1090198107309459. Epub 2007 Dec 12.
Zotero 插件